Analysis of amino acid parameters in the Resonant Recognition Model

Abstract

The Resonant Recognition Model (RRM) is a physicomathematical model developed for analysing protein and nucleic acid sequences. Previously, the electron-ion interaction potentials (EIIP) of amino acids have been used to determine the characteristic frequency of biologically related proteins. In this study, the effect of various other amino acid parameters on periodicity, obtained using the RRM, were assessed. Three functionally unrelated protein groups (glucagons, lysozymes and haemoglobins) were used as test examples. However, no single parameter was found to be a good representative of biological activity.