Impact of Serum Pro-calcitonin Level Among SARS-CoV-2 Infected Patients: Emphasizing on A Medullary Thyroid Cancer Survivor in Kolkata, India

R. Chatterjee, S. Chatterjee, S. Sikdar, A. Chowdhury, Debolina Bhattacharjee, Titlee Majumder, Nilanjan Mitra, Bithika Pramanik, B. Das, R. Ghosh
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Abstract

The coronavirus that causes severe acute respiratory syndrome (SARS-CoV-2) is a positive sense single stranded RNA (ssRNA) virus that first appeared in China and has spread throughout the world since late 2019. The SARS-CoV-2 virus causes a mild to severe respiratory infection that affects not just the lungs but also pancreas and other endocrine glands, as well as responsible for ischemic stroke and sexual dysfunctions. Serum pro-calcitonin (PCT) levels have been linked to the severity of coronavirus disease (COVID-19) in several investigations. According to our studies, high PCT levels are linked to a greater risk of severe COVID-19 infection in patients, as well as its involvement and role in a COVID-19 infected cancer survivor. This is the first study we are aware of from India that shows COVID-19 infected people should have regular PCT screening may help clinicians to plan intensive care unit (ICU) placement and detect any recurrence of past illness if any.
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SARS-CoV-2感染患者血清降钙素原水平的影响:以印度加尔各答的一名甲状腺髓样癌幸存者为重点
导致严重急性呼吸综合征(SARS-CoV-2)的冠状病毒是一种阳性单链RNA (ssRNA)病毒,最早出现在中国,自2019年底以来已在全球传播。SARS-CoV-2病毒引起轻度至重度呼吸道感染,不仅影响肺部,还影响胰腺和其他内分泌腺,并导致缺血性中风和性功能障碍。在一些调查中,血清降钙素原(PCT)水平与冠状病毒病(COVID-19)的严重程度有关。根据我们的研究,高PCT水平与患者严重感染COVID-19的风险增加有关,也与感染COVID-19的癌症幸存者的参与和作用有关。这是我们所知的第一项来自印度的研究表明,COVID-19感染者应该定期进行PCT筛查,这可能有助于临床医生计划重症监护病房(ICU)的安置,并发现过去疾病的复发(如果有的话)。
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