White Blood Cells Ratios in Patients with Acute Coronary Syndromes in Association with Hypertension and Diabetes Mellitus

Emergency Medical Service Pub Date : 2021-04-17 DOI:10.31435/RSGLOBAL_SR/30042021/7535

Iyad Alghzawi

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Abstract

The aim: The purpose of this study was to evaluate of white blood cells ratios in patients with ACS in association with arterial hypertension and 2 type Diabetes Mellitus. Material and Methods: In this observational cohort trial we observed of 184 patients with ACS. All patients were randomized into four groups: 1st group – 42 patients with ACS without AH or DM; 2nd group – 56 patients with ACS and previous AH; 3rd group – 42 patients with ACS and 2 type DM; and 4th group – 44 patients with ACS and AH and DM. We studied of leukocytes count and their subpopulation ratios: neutrophils to lymphocytes ratio (NLR), neutrophils to monocytes ratio (NMR), neutrophils to lymphocytes+monocytes ratio (N/LMR), lymphocytes to monocytes ratio (NMR). Results: The mean white blood cells count was significant higher in patients with ASC, compared with control group (p<0.001). In patients with ACS the elevated NMR and NLR were observed: 15.04±1.28 vs 11.09±0.43 in control group (p<0.05), and 3.34±0.20 vs 2.60±0.06 (p<0.05), respectively. No significant differences between WBC ratios were revealed in observed patients with ACS with or without AH and/or DM. Conclusion: ACS is characterized of raised NLR and NMR which could be indicators of poor prognosis

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高血压和糖尿病患者急性冠状动脉综合征的白细胞比率

目的:本研究的目的是评估与动脉高血压和2型糖尿病相关的ACS患者的白细胞比率。材料和方法:在这项观察性队列试验中，我们观察了184例ACS患者。所有患者随机分为四组:第一组- 42例ACS患者，无AH或DM;第二组:56例ACS合并既往AH患者;第三组:ACS合并2型糖尿病42例;第4组为44例ACS、AH和DM患者。研究白细胞计数及其亚群比:中性粒细胞与淋巴细胞比(NLR)、中性粒细胞与单核细胞比(NMR)、中性粒细胞与淋巴细胞+单核细胞比(N/LMR)、淋巴细胞与单核细胞比(NMR)。结果:ASC患者的平均白细胞计数明显高于对照组(p<0.001)。ACS患者核磁共振(NMR)和NLR升高:对照组为15.04±1.28 vs 11.09±0.43 (p<0.05)，对照组为3.34±0.20 vs 2.60±0.06 (p<0.05)。观察到的ACS合并AH和/或dm患者的WBC比值无显著差异。结论:ACS以NLR和NMR升高为特征，可作为预后不良的指标

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Emergency Medical Service

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