The Effect of Milk Thistle, Green Tea, and Cinnamon Beverages on Liver Enzymes of Operating Room Anesthesia Personnel

Vahid Kheirandish, Maysam Mard-Soltani, F. Mojab, Neda Shakerian, Farhad Nanaie
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Abstract

Background: Millions of health workers in operating rooms worldwide are exposed to inhaled anesthetics. However, the effects of continuous exposure to inhalational anesthetics are still controversial in many studies. Objectives: The present study investigated the effects of milk thistle, green tea, and cinnamon consumption on liver enzymes in operating room personnel. Methods: In this study, we investigated the effects of milk thistle tea, green tea, and cinnamon tea on liver enzymes in operating room staff in a controlled, double-blind study from 2019 to 2020. In two parallel groups, 62 subjects were randomly assigned to ingest the beverages the teas. Milk thistle, green tea, and cinnamon were taken daily for four weeks. During the intervention, all participants were educated about the importance of a balanced diet and physical activity. Results: The milk thistle, green tea, and cinnamon groups showed a significant statistical difference in reduced levels of AST, ALT, ALP, ALB, GGT, bilirubin, and ESR after four weeks (P value < 0.001). Conclusions: The results of this study demonstrated that ingesting green tea and cinnamon reduced liver enzymes in surgical personnel. Among the extracts, milk thistle had a greater effect on liver enzymes than the other two extracts. It can be concluded that the prescribed milk thistle extract can be considered a potential intervention to improve liver enzyme levels in surgical personnel to reduce the adverse effects of anesthetics.
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乳蓟、绿茶、肉桂饮料对手术室麻醉人员肝酶的影响
背景:全世界手术室中数百万卫生工作者暴露于吸入麻醉剂。然而,在许多研究中,持续暴露于吸入麻醉剂的影响仍然存在争议。目的:研究水飞蓟、绿茶和肉桂对手术室人员肝酶的影响。方法:采用2019 - 2020年双盲对照研究方法,研究了乳蓟茶、绿茶和肉桂茶对手术室工作人员肝酶的影响。在两个平行组中,62名受试者被随机分配饮用饮料和茶。他们每天服用奶蓟、绿茶和肉桂,持续四周。在干预期间,所有参与者都接受了均衡饮食和体育活动重要性的教育。结果:4周后,水飞蓟组、绿茶组、肉桂组AST、ALT、ALP、ALB、GGT、胆红素、ESR水平降低,差异均有统计学意义(P值< 0.001)。结论:本研究结果表明,摄入绿茶和肉桂可降低外科人员的肝酶。其中,水飞蓟提取物对肝酶的影响大于其他两种提取物。由此可见,处方水飞蓟提取物可作为一种潜在的干预措施,改善手术人员的肝酶水平,减少麻醉剂的不良反应。
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