Regulation of MT dynamics via direct binding of an Abl family kinase

Yuhan Hu, Wanqing Lyu, L. A. Lowery, A. Koleske
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引用次数: 11

Abstract

Genetic studies revealed that Abl family kinases interact functionally with microtubules, but the mechanism by which Abl kinases regulate microtubules remains unclear. Hu et al. provide the first evidence that the Abl family kinase Abl2 directly binds microtubules to regulate microtubule dynamics.
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通过Abl家族激酶的直接结合调控MT动力学
遗传学研究表明,Abl家族激酶与微管具有功能相互作用,但Abl激酶调节微管的机制尚不清楚。Hu等人提供了Abl家族激酶Abl2直接结合微管调节微管动力学的第一个证据。
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