Anti-Glomerular Basement Membrane Disease Following Nephrectomy

N. Droz, R. Hajj-Ali
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Abstract

A 51 year old female presented with rapidly progressive renal failure and diffuse alveolar hemorrhage following nephrectomy for retroperitoneal fibrosis. Anti-glomerular basement membrane (anti-GBM) antibodies returned strongly positive confirming a diagnosis of anti-GBM disease. She was treated with corticosteroids, plasma exchange and cyclophosphamide. To our knowledge, this is the first adult case of anti-GBM disease following nephrectomy.
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肾切除术后抗肾小球基底膜病
一例51岁女性患者在因腹膜后纤维化而行肾切除术后出现快速进展性肾衰竭和弥漫性肺泡出血。抗肾小球基底膜(抗gbm)抗体返回强阳性,证实了抗gbm疾病的诊断。患者接受皮质类固醇、血浆置换和环磷酰胺治疗。据我们所知,这是首例成人肾切除术后出现抗gbm疾病的病例。
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