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A Case of Severe Exercise Associated Hyponatremia after Running Marathon 马拉松后发生严重运动相关性低钠血症1例
Pub Date : 2020-12-27 DOI: 10.31038/ijnus.2020213
H. Kong, H. Tang, Jacky Man-Ho Wong, S. Fung
7.2 mmol/L, 85 µmol/L, and 2732 U/L respectively. Urine myoglobin was negative. White cell count was 17 x 10 9 /L, otherwise the complete blood count and liver function tests were normal. Further workup for hyponatremia were performed. Paired plasma osmolality, urine osmolality, and spot urine sodium checked 5 hours later were 244 mmol/Kg, 580 mmol/Kg, and 46 mmol/L respectively. There were no adrenal insufficiency or hypothyroidism. Deaths are with only 14 Abstract Exercise associated hyponatremia (EAH) can cause serious neurological manifestations. We report a case of EAH presented with convulsion and drowsiness after running marathon. The patient’s plasma sodium level on presentation was 119 mmol/L. He was given intravenous hypertonic saline infusion for 2 times. His conscious level improved after hypertonic saline and plasma sodium level corrected. He regained full consciousness 3 days after admission and was discharged in good condition. In this report, we reviewed the underlying pathophysiology, clinical features, risk factors, prevention measures, and treatment options of this disease entity. Early recognition of this disease entity and timely treatment with hypertonic saline is life saving.
分别为7.2 mmol/L、85µmol/L和2732 U/L。尿肌红蛋白呈阴性。白细胞计数为17 × 10 9 /L,其他全血细胞计数和肝功能检查均正常。进一步检查低钠血症。5小时后检测配对血浆渗透压、尿渗透压和尿钠点分别为244 mmol/Kg、580 mmol/Kg和46 mmol/Kg。无肾上腺功能不全或甲状腺功能减退。运动相关性低钠血症(EAH)可引起严重的神经系统症状。我们报告一例EAH患者在跑完马拉松后表现为抽搐和嗜睡。患者入院时血钠水平为119 mmol/L。静脉滴注高渗盐水2次。高渗生理盐水和血浆钠水平校正后,患者意识水平有所改善。入院3天后恢复完全意识,出院情况良好。在本报告中,我们回顾了潜在的病理生理、临床特征、危险因素、预防措施和治疗方案。早期识别这种疾病并及时用高渗盐水治疗可以挽救生命。
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引用次数: 0
The Effect of COVID-19 Pandemic on Urolithiasis Management and Urologists in the Gulf Countries: A Survey of Urologists in GCC 2019冠状病毒病大流行对海湾国家尿石症管理和泌尿科医生的影响:海湾国家泌尿科医生调查
Pub Date : 2020-08-25 DOI: 10.31038/ijnus.2020211
Al-Naimi, T. Ibrahim, Tariq F. Al-Shaiji, Abdulqadir Alzarooni, M. Banakhar, S. Al-Busaidy, Ayman, Raees, M. Moazin
Objective: To explore the effects of COVID-19 on urolithiasis management and on the medical practice of urologists in Gulf countries. Methods: A web-based survey was sent to urologists in the six countries in the Gulf Cooperation Council (GCC). The survey consisted of 23 questions about their working environment, urolithiasis management experience, and the policies of their facilities during the COVID-19 pandemic. Results: During the one-week survey period, responses were received from 191 urologists working in the six GCC countries. Responses were received from urologists in all six countries but the numbers differed markedly. Of the 191 urologists who responded, 160 (83.8%) were experienced urologists and 31 (16.2%) were urology residents. Eighty-four (44.0%) volunteered for COVID-19 management rather than urology, 22 (11.5%) were infected with COVID-19 and 38 (19.9%) sought mental health support. Clinical duties related to urolithiasis management were reduced for most of the urologists, with elective procedures postponed and urolithiasis management confined to emergency conditions. In the absence of COVID-19 infection, 67 (35.1%) preferred to actively manage ureteral stones, whereas the remaining urologists preferred less invasive methods, such as conservative or instant drainage. Conclusion: COVID-19 is hazardous to urologists in GCC countries, with 11.5% being infected and most reducing their clinical duties related to urolithiasis management. Although urolithiasis management in GCC countries during the COVID-19 pandemic was generally consistent with worldwide guidelines, some differences were observed,
目的:探讨2019冠状病毒病(COVID-19)对海湾国家泌尿科医生尿石症管理和医疗实践的影响。方法:对海湾合作委员会(GCC)六个国家的泌尿科医生进行网络调查。该调查包括23个问题,涉及他们的工作环境、尿石症管理经验以及2019冠状病毒病大流行期间他们的设施政策。结果:在为期一周的调查期间,收到了来自六个海湾合作委员会国家191名泌尿科医生的回复。从所有六个国家的泌尿科医生那里收到了反馈,但数量明显不同。在191名回应的泌尿科医生中,160名(83.8%)是有经验的泌尿科医生,31名(16.2%)是泌尿科住院医师。84人(44.0%)自愿参加COVID-19管理而不是泌尿科,22人(11.5%)感染COVID-19, 38人(19.9%)寻求心理健康支持。大多数泌尿科医生减少了与尿石症管理相关的临床职责,选择性手术被推迟,尿石症管理仅限于紧急情况。在没有COVID-19感染的情况下,67名(35.1%)泌尿科医生倾向于积极治疗输尿管结石,而其余泌尿科医生则倾向于微创方法,如保守或即时引流。结论:2019冠状病毒病对海湾合作委员会国家的泌尿科医生来说是危险的,11.5%的泌尿科医生被感染,大多数泌尿科医生减少了与尿石症管理相关的临床职责。尽管在2019冠状病毒病大流行期间,海湾合作委员会国家的尿石症管理总体上与国际指导方针一致,但也观察到一些差异,
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引用次数: 0
A New Tool for Assessing Bladder Outlet Obstruction 评估膀胱出口梗阻的新工具
Pub Date : 2020-01-25 DOI: 10.31038/ijnus.2019114
S. Emara
Objective: Assessing the role of transrectal Doppler ultrasound in estimating degree of bladder outlet obstruction, in patients with benign prostatic hyperplasia. Methods: Fifty two patients aged from 55 to 70with the clinical diagnosis of BPH were recruited. Patients with cancer prostate, neurogenic bladder, previous lower urinary tract intervention, were excluded. Urologic evaluation included, thorough history, IPSS, neurologic examination, digital rectal examination, urine analysis, PSA, uroflowmetry, transrectal doppler ultrasonography. The correlations were analysed between the resistive index of prostatic capsular artery, and maximum flow rate (Qmax). Results: A significant increase in RI correlated to decrease in Qmax (r= -0.398, p<0.016) was found. Also there was significant increase in RI correlated to increase in IPSS (r=0.535, p<0.001). AS regard Qmax, there was significant decrease in Qmax correlated to increase in IPSS (r=-0.654, p<0.001). Conclusion: Transrectal Doppler can be used as a tool to measure degree of bladder outlet obstruction, through measuring resistive index of prostatic capsular artery.
目的:探讨经直肠多普勒超声在判断良性前列腺增生患者膀胱出口梗阻程度中的作用。方法:选取临床诊断为前列腺增生的患者52例,年龄55 ~ 70岁。排除前列腺癌、神经源性膀胱、既往下尿路干预的患者。泌尿系统检查包括:详细病史、IPSS、神经系统检查、直肠指检、尿液分析、PSA、尿流仪、经直肠多普勒超声。分析前列腺包膜动脉阻力指数与最大血流率(Qmax)的相关性。结果:RI升高与Qmax降低相关(r= -0.398, p<0.016)。RI的增加与IPSS的增加相关(r=0.535, p<0.001)。Qmax降低与IPSS升高相关(r=-0.654, p<0.001)。结论:经直肠多普勒检测前列腺包膜动脉阻力指数,可作为检测膀胱出口梗阻程度的工具。
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引用次数: 0
A LIFE IN UROLOGY: Privilege, Obligation and Reward 泌尿外科的生活:特权、义务和回报
Pub Date : 2020-01-13 DOI: 10.31038/ijnus.2019113
Tomohiko Koyanag, T. Koyanagi
A life of an urologist, who thrived in academia after early postgraduate training in the US, was presented. Through this somewhat “game-changing” pathway lessons learned and advices were given for young generation of urologists.
一个泌尿科医生的生活,谁在美国早期研究生培训后,在学术界蓬勃发展,介绍。通过这种“改变游戏规则”的途径,为年轻一代的泌尿科医生提供了经验教训和建议。
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引用次数: 0
Anti-Glomerular Basement Membrane Disease Following Nephrectomy 肾切除术后抗肾小球基底膜病
Pub Date : 2019-12-25 DOI: 10.31038/ijnus.2019112
N. Droz, R. Hajj-Ali
A 51 year old female presented with rapidly progressive renal failure and diffuse alveolar hemorrhage following nephrectomy for retroperitoneal fibrosis. Anti-glomerular basement membrane (anti-GBM) antibodies returned strongly positive confirming a diagnosis of anti-GBM disease. She was treated with corticosteroids, plasma exchange and cyclophosphamide. To our knowledge, this is the first adult case of anti-GBM disease following nephrectomy.
一例51岁女性患者在因腹膜后纤维化而行肾切除术后出现快速进展性肾衰竭和弥漫性肺泡出血。抗肾小球基底膜(抗gbm)抗体返回强阳性,证实了抗gbm疾病的诊断。患者接受皮质类固醇、血浆置换和环磷酰胺治疗。据我们所知,这是首例成人肾切除术后出现抗gbm疾病的病例。
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引用次数: 0
Role of Corticosteroids in Rhabdomyolysis 皮质类固醇在横纹肌溶解中的作用
Pub Date : 2019-12-01 DOI: 10.31038/ijnus.2019111
Shivam Patel, S. Padala, A. Mohammed, R. Kapoor
Rhabdomyolysis is a medical condition that involves rapid breakdown of injured skeletal muscle, resulting in the leakage of muscle contents into the circulation. The most common causes of rhabdomyolysis include trauma, muscle overexertion, alcohol abuse, and the use of certain medications and illicit drugs. The goal of the treatment is usually to maintain adequate volume repletion to prevent renal failure and metabolic abnormalities. Hemodialysis is an alternative therapy to prevent renal failure when there is no response to aggressive intravenous hydration. We present a case of severe rhabdomyolysis that was refractory to the current standard of care and showed dramatic improvement with corticosteroids.
横纹肌溶解是一种医学病症,涉及受伤的骨骼肌迅速分解,导致肌肉内容物渗漏到循环中。横纹肌溶解最常见的原因包括创伤、肌肉过度运动、酗酒、使用某些药物和非法药物。治疗的目标通常是维持足够的容量补充,以防止肾功能衰竭和代谢异常。血液透析是一种替代疗法,以防止肾功能衰竭时,没有反应积极静脉补液。我们提出了一个严重横纹肌溶解的病例,目前的标准护理是难治的,并在皮质类固醇治疗后表现出显著的改善。
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引用次数: 0
期刊
Integrative Journal of Nephro-Urology Studies
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