Chengjun Huang, J. Putzeys, J. Ye, G. Reekmans, K. Verhaegen, L. Lagae, K. Verstreken, G. Borghs
{"title":"Lable-free biosensor based on localized surface plasmon resonance in a multi-channel microfluidic chip","authors":"Chengjun Huang, J. Putzeys, J. Ye, G. Reekmans, K. Verhaegen, L. Lagae, K. Verstreken, G. Borghs","doi":"10.1109/SAS.2009.4801774","DOIUrl":null,"url":null,"abstract":"A label-free biosensor based on localized surface plasmon resonance (LSPR) was developed. A multi-channel microfluidic chip was integrated with the sensor, providing referencing channel to minimize noise level and improving the throughput. With a CCD as a detector, a sensitivity of 10™4 RIU was demonstrated. The adsorption of S-layer protein was detected successfully by the sensor system.","PeriodicalId":410885,"journal":{"name":"2009 IEEE Sensors Applications Symposium","volume":"42 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2009 IEEE Sensors Applications Symposium","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/SAS.2009.4801774","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
A label-free biosensor based on localized surface plasmon resonance (LSPR) was developed. A multi-channel microfluidic chip was integrated with the sensor, providing referencing channel to minimize noise level and improving the throughput. With a CCD as a detector, a sensitivity of 10™4 RIU was demonstrated. The adsorption of S-layer protein was detected successfully by the sensor system.
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