Hematological Findings in COVID-19 and Insights to Stem Cell Therapy: From Bench to Practice

Abstract

Context: As the COVID-19 was spreading to all countries, its manifestations were identifying gradually, which were related to several organs. Evidence Acquisition: COVID-19 is associated with distinct hematological changes, increased serum inflammatory markers, and coagulopathy. Most of these changes are related to the patients’ prognosis and mortality, particularly in those with severe disease. Results: Firstly, we discussed the associations between COVID-19 clinical features and complications, and secondly, its hematological findings and coagulopathy are investigated. Conclusions: Such associations not only may shed light on our prognostic view of patients with COVID-19 but also will entail significant therapeutic implications. One of its key implications is to utilize the mesenchymal stem cells (MSCs) to treat patients with COVID-19. Herein, this kind of novel therapy will be discussed, as well.