Elevated Level of Serum Vitamin D Reduce the Chance of Latent Genital Tuberculosis

Abira Datta, B. Bhattacharya, R. Chowdhury, S. Chatterjee, S. Chowdhury
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Abstract

Aim: To explore the possibility of risk factor between latent genital tuberculosis with association of low secretion anti-mullerian hormone(AMH) and low level of Vitamin D for infertility. Design: Retrospective study was done in the reproductive medicine unit of Calcutta Fertility Mission, Kolkata-700019, and India Result: From January 2017 to January 2019, total 150 Subjects (n= 75 TB-PCR positive and n=75 TB-PCR negative cases as control) were included in this study on the basis of inclusion and exclusion criteria. We have found that mean value of AMH and Vitamin D were higher in PCR negative group than positive group. Various level of AMH and Vitamin D concentration for PCR positive and negative cases were statistically significant (p-value < 0.01). Conclusion: Our finding is that vitamin D deficiency is highly prevalent not only in active tuberculosis but also in latent genital tuberculosis subjects and serum Vitamin D level may help in treatment of latent genital tuberculosis. Elevated level of Vitamin D in serum may rule out latent tuberculosis.
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血清维生素D水平升高可减少潜伏性生殖器结核病的机会
目的:探讨潜伏性生殖器结核与低分泌抗苗勒管激素(AMH)和低水平维生素D相关的不育危险因素的可能性。设计:回顾性研究在加尔各答-700019和印度加尔各答生育中心生殖医学单元进行。结果:2017年1月至2019年1月,根据纳入和排除标准,共纳入150名受试者(n= 75例TB-PCR阳性和n=75例TB-PCR阴性作为对照)。我们发现PCR阴性组AMH和维生素D的平均值高于阳性组。不同水平AMH和维生素D浓度在PCR阳性和阴性病例中差异均有统计学意义(p值< 0.01)。结论:维生素D缺乏症不仅在活动性肺结核患者中普遍存在,而且在潜伏性生殖器肺结核患者中也普遍存在,血清维生素D水平可能有助于潜伏性生殖器肺结核的治疗。血清中维生素D水平升高可排除潜伏性肺结核。
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