{"title":"Predisposing Factors to HBV Among Pregnant Women Attending Some Hospitals in Suburbs of Kano, Nigeria","authors":"O. A. Abulude, Farouk Umar Sadisu, Ismai’la Ahmed","doi":"10.31487/j.cmr.2019.01.02","DOIUrl":null,"url":null,"abstract":"Hepatitis B virus (HBV) when transmitted vertically can be severe on neonates and life threatening. Among\nothers, risk factors for HBV include unprotected sex, needle-stick injuries and blood transfusion. The study\nwas conducted to determine the seroprevalence of HBV markers and associated risk factors among one\nhundred and sixty consenting pregnant women attending some hospitals in Kano, Nigeria. Using enzymelinked immunoassay, sera were screened for HBV sero-markers and structured questionnaires were\nadministered to obtain sociodemographic data and possible predisposing factors to HBV infection. Of the\nfive HBV markers known, participants tested positive for four, which include HBsAg, HBsAb, HBeAb and\nHBcAb. All were seronegative for HBeAg. Ninety three percent (93.1%) tested positive for at least one\nHBV marker and 6.9% were seronegative for all markers. Among those that tested positive for HBsAg,\n54.5% (p=0.33) were housewives, 36.4% (p=0.53) had only primary school education, 72.7% (p=0.14) were\nmiddle-class, none had previous knowledge of HBV infection and its mode of transmission, 54.5% (p=0.14)\nregularly shares sharp objects, 45.5% (p=0.37) had ear or nose piercing, and 9.1% (p=0.01) regularly shares\ntowel and underwear. A large percentage of the study group had history of the infection while only 1.3% of\nthe subjects were vaccinated. Sociodemographic background of the participants, low vaccination coverage\nand certain risk factors like the sharing of unsterilized sharp objects seem to aid the moderately high\nprevalence of HBV in this study. The study also revealed that the risk of mother-to-child HBV transmission\nis low in the study area and that incomplete vaccination may not confer artificial immunity against HBV\ninfection.\n","PeriodicalId":364792,"journal":{"name":"Clinical Microbiology and Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Microbiology and Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31487/j.cmr.2019.01.02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Hepatitis B virus (HBV) when transmitted vertically can be severe on neonates and life threatening. Among
others, risk factors for HBV include unprotected sex, needle-stick injuries and blood transfusion. The study
was conducted to determine the seroprevalence of HBV markers and associated risk factors among one
hundred and sixty consenting pregnant women attending some hospitals in Kano, Nigeria. Using enzymelinked immunoassay, sera were screened for HBV sero-markers and structured questionnaires were
administered to obtain sociodemographic data and possible predisposing factors to HBV infection. Of the
five HBV markers known, participants tested positive for four, which include HBsAg, HBsAb, HBeAb and
HBcAb. All were seronegative for HBeAg. Ninety three percent (93.1%) tested positive for at least one
HBV marker and 6.9% were seronegative for all markers. Among those that tested positive for HBsAg,
54.5% (p=0.33) were housewives, 36.4% (p=0.53) had only primary school education, 72.7% (p=0.14) were
middle-class, none had previous knowledge of HBV infection and its mode of transmission, 54.5% (p=0.14)
regularly shares sharp objects, 45.5% (p=0.37) had ear or nose piercing, and 9.1% (p=0.01) regularly shares
towel and underwear. A large percentage of the study group had history of the infection while only 1.3% of
the subjects were vaccinated. Sociodemographic background of the participants, low vaccination coverage
and certain risk factors like the sharing of unsterilized sharp objects seem to aid the moderately high
prevalence of HBV in this study. The study also revealed that the risk of mother-to-child HBV transmission
is low in the study area and that incomplete vaccination may not confer artificial immunity against HBV
infection.