Results of transsphenoidal endoscopic removal of ACTH-secreting pituitary adenomas

Abstract

The article presents the results of surgical treatment of patients who underwent endoscopic transsphenoidal adenomectomy for ACTH-secreting pituitary adenomas in the Neurosurgical Department of the Pavlov First Saint Petersburg State Medical University from 2015 to 2022. The analysis of patients was carried out according to the following criteria: clinical manifestations of the disease, the nature of tumor growth according to the MRI study, positive results of surgical treatment, postoperative complications. Effective treatment of ACTH-secreting pituitary adenomas is necessary as this tumor is associated with the development of Itsenko-Cushing's disease, and in the absence of adequate and timely treatment and in case of preservation of hypercorticism, the 5‑year mortality of these patients exceeds that of general population, reaching 50%.