A. Lukyanov, D. Donskoy, V. Filipović, T. B. Asten
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Abstract
Reactions of neutralization occur with significant nonlinearity, which determines the control algorithms in the mode of periodic dosing of a volume of acid or alkali. Such regulation may have little effectiveness due to the fluctuation or impossibility of regulation due to insufficient or excessive concentration. This article precisely regulates the hydrogen index in mini- bioreactors and proposes the use of a digital model of the acidity management system for the selection of concentrations of topped-up solutions, determination of the regulation methodology, and improvement of accuracy pH regulation in an in vitro mini-model of the gastrointestinal tract (GIT) of a static type.
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