Evaluation of In-vitro Antibacterial and Anthelmintic Activities of Sauropus androgynus (Phyllanthaceae) Plant Extracts

Palaksha Mn
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引用次数: 1

Abstract

The present study was carried out to evaluate the qualitative analysis of various phytochemicals and in-vitro evaluation of antibacterial and anthelmintic activities of Ethanolic leaf extracts of Sauropus androgynus (Phyllanthaceae). The extracts were subjected to preliminary phytochemical screening for the identification of different phytoconstituents, the leaves indicated the presence of proteins, resins, steroids, tannins, glycosides, reducing sugar, carbohydrates, saponins, sterols, terpenoids, acidic compounds, cardiac glycosides, catechol, phenols, alkaloids, flavanoids. The different concentrations of Ethanolic extracts were subjected to antibacterial screening against various Gram positive and Gram negative bacteria and the results were compared with that of standard drug Gentamycin. Different concentrations of leaf extracts were tested to evaluate Anthelmintic activity using Sauropus androgynus (Indian earthworm). The extracts was found to possess vermifuge and vermicidal activity and the results were compared with standard drug Albendazole.
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雌雄同体龙柏(Phyllanthaceae)植物提取物体外抗菌和驱虫活性评价
本研究对雌雄同体龙柏(Sauropus androgynus, Phyllanthaceae)乙醇叶提取物的多种植物化学成分进行了定性分析,并对其体外抗菌和驱虫药活性进行了评价。对提取液进行初步的植物化学筛选,鉴定出不同的植物成分,叶片显示出蛋白质、树脂、类固醇、单宁、糖苷、还原糖、碳水化合物、皂苷、甾醇、萜类、酸性化合物、心苷、儿茶酚、酚类、生物碱、黄酮类。对不同浓度乙醇提取物进行抑菌筛选,筛选出革兰氏阳性菌和革兰氏阴性菌,并与标准药庆大霉素进行比较。以不同浓度的雌雄同体沙蚕(Sauropus androgynus)为研究对象,对其叶片提取物的驱虫活性进行了研究。发现其提取物具有驱虫和杀虫活性,并与标准药物阿苯达唑进行了比较。
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