The use of plant-based medicines, health products, food supplements, and cosmetics is being increased nowadays due to their active and healthy ingredients. 1,8-cineole is a natural monoterpene, also known as eucalyptol. It is a major compound of many plant essential oils, mainly extracted from Eucalyptus globulus, Elettaria cardamom, Amomum subulatum Roxb. 1,8-cineole has recently been identified as a rhizosphere volatile in Arabidopsis, is well known as an allelopathic agent from Salvia and Artemisia. These are traditionally used as herbal medicine in Ayurveda, Homeopathy, Naturopathy, Siddha, Unani and Yoga worldwide. They are indigenous plant native to India and are rich in bioactive molecules like alkaloids, anthocyanins, chlorogenic acids, coumarins, flavonoids, lignans, phenolic acids, saponins and glycosidic substitutes, tannins and terpenoids. Hence they are used to cure a wide range of diseases and act as a good anti-diabetic agent. 1,8-Cineole is a colourless liquid and found is many medicinal plants. This review aims to summarize the pharmacological bio-activities reported in literature. A system review was collected from various public databases such as NCBI, EMBASE and other reported research articles. Methodologies were focused on 1,8-Cineole anti-inflammatory property, gastroprotective mechanism, anti-microbial property, Anti-proliferative and Hepatoprotective mechanism. The present review aims to summarize and consolidate the biological properties of 1,8-Cineole.
{"title":"1,8-Cineole an Underappreciated Anti Inflammatory Therapeutic","authors":"Ramya Ak","doi":"10.23880/ipcm-16000238","DOIUrl":"https://doi.org/10.23880/ipcm-16000238","url":null,"abstract":"The use of plant-based medicines, health products, food supplements, and cosmetics is being increased nowadays due to their active and healthy ingredients. 1,8-cineole is a natural monoterpene, also known as eucalyptol. It is a major compound of many plant essential oils, mainly extracted from Eucalyptus globulus, Elettaria cardamom, Amomum subulatum Roxb. 1,8-cineole has recently been identified as a rhizosphere volatile in Arabidopsis, is well known as an allelopathic agent from Salvia and Artemisia. These are traditionally used as herbal medicine in Ayurveda, Homeopathy, Naturopathy, Siddha, Unani and Yoga worldwide. They are indigenous plant native to India and are rich in bioactive molecules like alkaloids, anthocyanins, chlorogenic acids, coumarins, flavonoids, lignans, phenolic acids, saponins and glycosidic substitutes, tannins and terpenoids. Hence they are used to cure a wide range of diseases and act as a good anti-diabetic agent. 1,8-Cineole is a colourless liquid and found is many medicinal plants. This review aims to summarize the pharmacological bio-activities reported in literature. A system review was collected from various public databases such as NCBI, EMBASE and other reported research articles. Methodologies were focused on 1,8-Cineole anti-inflammatory property, gastroprotective mechanism, anti-microbial property, Anti-proliferative and Hepatoprotective mechanism. The present review aims to summarize and consolidate the biological properties of 1,8-Cineole.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132494173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
According to the World Health Organization, 80% of the world’s population relies mostly on traditional remedies including the use of plant extracts or active components. India’s mega-biodiversity and knowledge of rich historic traditional systems of medicine (Ayurveda, Siddha, Unani, Amchi, and local health traditions) give a solid foundation for the use of a wide range of plants in general healthcare and the treatment of common disorders. Tinospora Cordifolia is a Deciduous woody climbing shrub found in India, China, and Africa. It is a member of the Menispermaceae family. This plant’s pharmacological importance stems mostly from its root, stem, and leaf. It contains a variety of photoactive chemicals, including alkaloids, steroids, glycosides, lactones, polysaccharides, and others. Practically every portion of the plant has immunomodulatory effects. It is a significant medicinal plant used in Ayurveda medicine to treat colds, fevers, diabetes, and even rheumatoid arthritis.
{"title":"Phytopharmacological Perspectives of Tinospora cordifolia Chemical Constituents and Medicinal Properties","authors":"Kagne Ss","doi":"10.23880/ipcm-16000235","DOIUrl":"https://doi.org/10.23880/ipcm-16000235","url":null,"abstract":"According to the World Health Organization, 80% of the world’s population relies mostly on traditional remedies including the use of plant extracts or active components. India’s mega-biodiversity and knowledge of rich historic traditional systems of medicine (Ayurveda, Siddha, Unani, Amchi, and local health traditions) give a solid foundation for the use of a wide range of plants in general healthcare and the treatment of common disorders. Tinospora Cordifolia is a Deciduous woody climbing shrub found in India, China, and Africa. It is a member of the Menispermaceae family. This plant’s pharmacological importance stems mostly from its root, stem, and leaf. It contains a variety of photoactive chemicals, including alkaloids, steroids, glycosides, lactones, polysaccharides, and others. Practically every portion of the plant has immunomodulatory effects. It is a significant medicinal plant used in Ayurveda medicine to treat colds, fevers, diabetes, and even rheumatoid arthritis.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"28 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128893633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arthritis is a type of autoimmune disorder and a major cause of disability throughout the world. Rheumatoid arthritis the denaturation of protein is one of the causes. In our present study, methanolic extract of combination of plant (Tinospora cordifolia (Thunb.) Miers, Curcuma longa L., Pongamia pinnata (L.) Panigrahi, Emblica officinalis L., Piper nigrum L.). Extracts inhibited heat induced protein denaturation and may be one of the reasons of possessing anti-arthritic activity. Methanolic extracts of different formulation for their antiarthritic activity against denaturation of bovine serum albumin. Result and attributed the 15 formulation out of F2 formulation possessed highly denaturation of protein. The denaturation of protein F2formulation presence of active principle such as alkaloids, flavonoids, saponins and terpenoids and HPTLC analysis major 2 bioactive compounds present which are responsible for this activity. GC-MS analysis of methanol extracts identified major bioactive with peak area 36.92 % is maximum in F2 formulation (10mg/10ml). In fact, herbal plants formulation of five plants for the F2 formulation are being used widely as medicine around decades for treatment of arthritic disease. Herbal medicine constitutes important resources for the treatment of arthritis disease.
{"title":"Evaluation of Effect on Combination of Five Medicinal Plants Extracts on Denaturation of Protein - A Remedy of Arthritis Disease","authors":"Ishnava K","doi":"10.23880/ipcm-16000233","DOIUrl":"https://doi.org/10.23880/ipcm-16000233","url":null,"abstract":"Arthritis is a type of autoimmune disorder and a major cause of disability throughout the world. Rheumatoid arthritis the denaturation of protein is one of the causes. In our present study, methanolic extract of combination of plant (Tinospora cordifolia (Thunb.) Miers, Curcuma longa L., Pongamia pinnata (L.) Panigrahi, Emblica officinalis L., Piper nigrum L.). Extracts inhibited heat induced protein denaturation and may be one of the reasons of possessing anti-arthritic activity. Methanolic extracts of different formulation for their antiarthritic activity against denaturation of bovine serum albumin. Result and attributed the 15 formulation out of F2 formulation possessed highly denaturation of protein. The denaturation of protein F2formulation presence of active principle such as alkaloids, flavonoids, saponins and terpenoids and HPTLC analysis major 2 bioactive compounds present which are responsible for this activity. GC-MS analysis of methanol extracts identified major bioactive with peak area 36.92 % is maximum in F2 formulation (10mg/10ml). In fact, herbal plants formulation of five plants for the F2 formulation are being used widely as medicine around decades for treatment of arthritic disease. Herbal medicine constitutes important resources for the treatment of arthritis disease.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123854708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ethnopharmacological relevance: Platycerium bifurcatum (CAV.) C. Chr., Commonly known as staghorn fern is an epiphytic plant with diverse medicinal uses, such as anti-ulcer remedy, treating oedema, coughs and hypertension. This research was aim at evaluating the pharmacognostic profile of P. Bifurcatum. Methods: The fresh and air-dried plant materials were evaluated for microscopic characters, ash values, extractive values, moisture content and phytoconstituents. Results: Pharmacognostic evaluation revealed two shape of leaves, one round and the other forked-like shape, dark and light green colour, slightly coarse texture at the abaxial surface and hairy due to the trichome at the adaxial surface, reticulate leaf venation and margin entire, presence non- grandular stellate trichomes at the lower epidermal layer, spongy mesopghyll, collenchyma cells, vascular bundles straight type of epidermal cell wall, anisocytes stomata. Moisture content of 6.283%, total ash value of 8.25% within the standard range, acid insoluble ash of 1%, water soluble of 6.0% and phytochemical screening analysis shows the presence of phenolic, saponins, glycosides and triterpenoid constituents. Conclusion: this study reports the first time the pharmacognostic properties of P. bifurcatum.
{"title":"Pharmacognostic Evaluation of Platycerium bifurcatum (Cav.) C. Chr. (Polypodiaceae)","authors":"S. M","doi":"10.23880/ipcm-16000234","DOIUrl":"https://doi.org/10.23880/ipcm-16000234","url":null,"abstract":"Ethnopharmacological relevance: Platycerium bifurcatum (CAV.) C. Chr., Commonly known as staghorn fern is an epiphytic plant with diverse medicinal uses, such as anti-ulcer remedy, treating oedema, coughs and hypertension. This research was aim at evaluating the pharmacognostic profile of P. Bifurcatum. Methods: The fresh and air-dried plant materials were evaluated for microscopic characters, ash values, extractive values, moisture content and phytoconstituents. Results: Pharmacognostic evaluation revealed two shape of leaves, one round and the other forked-like shape, dark and light green colour, slightly coarse texture at the abaxial surface and hairy due to the trichome at the adaxial surface, reticulate leaf venation and margin entire, presence non- grandular stellate trichomes at the lower epidermal layer, spongy mesopghyll, collenchyma cells, vascular bundles straight type of epidermal cell wall, anisocytes stomata. Moisture content of 6.283%, total ash value of 8.25% within the standard range, acid insoluble ash of 1%, water soluble of 6.0% and phytochemical screening analysis shows the presence of phenolic, saponins, glycosides and triterpenoid constituents. Conclusion: this study reports the first time the pharmacognostic properties of P. bifurcatum.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123175717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mycobacterium tuberculosis is the name of the bacterium that causes tuberculosis (TB), which typically affects the lungs. Lifetime exposure to TB bacteria increases the risk of developing TB by 5–10%. A person’s likelihood of getting sick rises if they lead an unhealthy lifestyle or have a compromised immune system. A person may take several months before showing symptoms of active TB disease. As a result, getting medical help may take longer, and the virus may spread to more people. Rifampicin, isoniazid, pyrazinamide, and ethambutol are given as part of the traditional treatment for pulmonary TB during the first two months, and then rifampicin and isoniazid are given for the following four months. For the treatment of multidrugresistant TB, levofloxacin, moxifloxacin, and bedaquiline are suggested.
{"title":"Overview of the Complexities in Diagnosing Treating and Preventing Tuberculosis along with the Most Effective Dosage Plans","authors":"Awan Sj","doi":"10.23880/ipcm-16000236","DOIUrl":"https://doi.org/10.23880/ipcm-16000236","url":null,"abstract":"Mycobacterium tuberculosis is the name of the bacterium that causes tuberculosis (TB), which typically affects the lungs. Lifetime exposure to TB bacteria increases the risk of developing TB by 5–10%. A person’s likelihood of getting sick rises if they lead an unhealthy lifestyle or have a compromised immune system. A person may take several months before showing symptoms of active TB disease. As a result, getting medical help may take longer, and the virus may spread to more people. Rifampicin, isoniazid, pyrazinamide, and ethambutol are given as part of the traditional treatment for pulmonary TB during the first two months, and then rifampicin and isoniazid are given for the following four months. For the treatment of multidrugresistant TB, levofloxacin, moxifloxacin, and bedaquiline are suggested.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123701402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emotional Intelligence (EI) has always been relevant in studies and investigations. It has been useful in various clinical and non-clinical domains of profession. The present article is a comprehensive narrative review especially in the context of mental health services. The authors have explored major studies conducted in last three decades and available on various sources like PubMed, Mendeley, google scholar, Cochrane, Psychinfo, Research Gate and APA Psychnet. In addition, a few additional published book chapters have also been reviewed on interventional research to be useful and incorporated. Finally, major methodological limitations and conclusions focus on a need for more representative research to understand the concept with special reference to mental health, have been incorporated.
{"title":"Whither Emotional Intelligence in Mental Healthcare","authors":"Prakash A","doi":"10.23880/ipcm-16000237","DOIUrl":"https://doi.org/10.23880/ipcm-16000237","url":null,"abstract":"Emotional Intelligence (EI) has always been relevant in studies and investigations. It has been useful in various clinical and non-clinical domains of profession. The present article is a comprehensive narrative review especially in the context of mental health services. The authors have explored major studies conducted in last three decades and available on various sources like PubMed, Mendeley, google scholar, Cochrane, Psychinfo, Research Gate and APA Psychnet. In addition, a few additional published book chapters have also been reviewed on interventional research to be useful and incorporated. Finally, major methodological limitations and conclusions focus on a need for more representative research to understand the concept with special reference to mental health, have been incorporated.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132892079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Having suffered from a global epidemic of Covid19 mutants and variants, the entire world has turned its attention and hope to natural treatments that can keep the immune system active and strong. Recent research on some herbal preparations promises high hopes that they may be potential candidates for developing effective and safe immune-boosting drugs. Considering that Turkey has the richest flora of Europe and the Middle East and has an invaluable ethnomedical background, it offers a treasure-worthy potential for serious researchers. 128 plant taxa belonging to 41 families were determined from 99 works carried out in different regions of Turkey. Of these, only 60 (46.9%) were found to be responded to in experimental studies worldwide on immune system enhancement and other similar activities. Quercetin (10.3%), β-glucan, and catechin (5.1%) emerged as the most common active substances among 39 identified active substances. Urtica dioica (39.4%), Rosa canina (34.3%), and Punica granatum (17.2%) were recorded as the most used plants in Turkey. In addition, Phoenix dactylifera has appeared as the taxon with having more active compounds in the literature. This study presents the first national inventory of immune-boosting plants that are regularly used in traditional Turkish medicine, not only against Covid-19 but for the prevention and treatment of epidemic diseases in general. We present 68 (53.1%) plants whose effective immune-stimulating and strengthening properties have been confirmed in experimental studies in the world literature as ready-made material to the relevant pharmacological sectors.
{"title":"Immune-Boosting Plants Used in Turkish Folk Medicine and their Potential against COVID-19","authors":"Sargin Sa","doi":"10.23880/ipcm-16000232","DOIUrl":"https://doi.org/10.23880/ipcm-16000232","url":null,"abstract":"Having suffered from a global epidemic of Covid19 mutants and variants, the entire world has turned its attention and hope to natural treatments that can keep the immune system active and strong. Recent research on some herbal preparations promises high hopes that they may be potential candidates for developing effective and safe immune-boosting drugs. Considering that Turkey has the richest flora of Europe and the Middle East and has an invaluable ethnomedical background, it offers a treasure-worthy potential for serious researchers. 128 plant taxa belonging to 41 families were determined from 99 works carried out in different regions of Turkey. Of these, only 60 (46.9%) were found to be responded to in experimental studies worldwide on immune system enhancement and other similar activities. Quercetin (10.3%), β-glucan, and catechin (5.1%) emerged as the most common active substances among 39 identified active substances. Urtica dioica (39.4%), Rosa canina (34.3%), and Punica granatum (17.2%) were recorded as the most used plants in Turkey. In addition, Phoenix dactylifera has appeared as the taxon with having more active compounds in the literature. This study presents the first national inventory of immune-boosting plants that are regularly used in traditional Turkish medicine, not only against Covid-19 but for the prevention and treatment of epidemic diseases in general. We present 68 (53.1%) plants whose effective immune-stimulating and strengthening properties have been confirmed in experimental studies in the world literature as ready-made material to the relevant pharmacological sectors.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127761327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stigmasterol (STG) is steroid alcohol that belongs to the group of phytosterols of the plant. It has different biological properties and considered a popular medicinal compound throughout the world. STG has established and emerging health benefits including anti-inflammatory activity, immunomodulatory effect, antiviral, antimicrobial, antifungal activities, possess positive modulatory effect on CNS, anticancer effect, hepatoprotective, antioxidant, antidiabetic, acaricidal activities. STG also has some negative and toxic effects such as accumulation of STG causes cardiac injury thereby causing mortality. This review overall describes the structure, source, function, mode of action and various pharmacological properties so that it can serve as a reference tool for other investigators working in the area.
{"title":"Stigmasterol in Health and Disease: A Review","authors":"Biswas Sj","doi":"10.23880/ipcm-16000231","DOIUrl":"https://doi.org/10.23880/ipcm-16000231","url":null,"abstract":"Stigmasterol (STG) is steroid alcohol that belongs to the group of phytosterols of the plant. It has different biological properties and considered a popular medicinal compound throughout the world. STG has established and emerging health benefits including anti-inflammatory activity, immunomodulatory effect, antiviral, antimicrobial, antifungal activities, possess positive modulatory effect on CNS, anticancer effect, hepatoprotective, antioxidant, antidiabetic, acaricidal activities. STG also has some negative and toxic effects such as accumulation of STG causes cardiac injury thereby causing mortality. This review overall describes the structure, source, function, mode of action and various pharmacological properties so that it can serve as a reference tool for other investigators working in the area.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122502388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Branton, M. Trivedi, Dahryn Trivedi, G. Nayak, S. Jana
Berberine chloride is an isoquinoline alkaloid that has antimicrobial activity against bacteria, viruses, chlamydia, fungi, protozoans, and helminths, etc. The study was designed with the aim to evaluate the influence of the Trivedi Effect®- Consciousness Energy Healing Treatment on the physicochemical and thermal properties of berberine chloride by using modern analytical techniques. For this study, the berberine chloride sample was divided into two parts among which, one part was named as control as no Biofield Energy Treatment was given to it; while the other part received the Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Alice Branton and named as the Biofield Energy Treated sample. The PXRD results revealed some changes in the Bragg’s angle of peaks along with - 7.24% to 188.78% alterations in the peak intensities and -65.88% to 135.42% changes in the crystallite sizes of the treated sample. Also, there was 1.91% decrease in the average crystallite size of the treated sample compared to the control sample. The particle size of the treated sample was significantly reduced by 20.16% (d10), 17.21% (d50), 27.53% (d90), and 27.36% {D(4,3)}; along with 15.31% increase in the specific surface area compared with the control sample. The total weight loss was significantly reduced by 25.81%; however, the residue amount was significantly increased by 55.04% in the treated sample compared to the control sample. Besides, the DSC thermogram showed four peaks, in which the peak temperatures of the treated sample corresponding to 1st, 2nd, 3rd, and 4th peak were altered by -2.26%, 3.55%, - 4.50%, and -0.69%, respectively. Moreover, the latent heat for 1st, 2nd, 3rd, and 4th peak of the treated sample were significantly reduced by 24.04%, 42.44%, 44.26%, and 47.78%, respectively, compared with the control sample. The results showed that the Trivedi Effect®-Consciousness Energy Healing Treatment might help in improving the solubility, absorption, and bioavailability of berberine chloride compared with the control sample. Hence, the Consciousness Energy Healing Treatment would be useful for designing the novel nutraceutical/pharmaceutical formulations of berberinechloride with improved drug profile for the treatment of various microbial diseases and disorders such as diarrhea, gastroenteritis, hypertension, tumor, malaria, hyperglycemia, inflammation, arrhythmia, infections, etc.
{"title":"Study of the Effect of Consciousness Energy Healing Treatment on the Natural Product Berberine Chloride","authors":"A. Branton, M. Trivedi, Dahryn Trivedi, G. Nayak, S. Jana","doi":"10.23880/IPCM-16000154","DOIUrl":"https://doi.org/10.23880/IPCM-16000154","url":null,"abstract":"Berberine chloride is an isoquinoline alkaloid that has antimicrobial activity against bacteria, viruses, chlamydia, fungi, protozoans, and helminths, etc. The study was designed with the aim to evaluate the influence of the Trivedi Effect®- Consciousness Energy Healing Treatment on the physicochemical and thermal properties of berberine chloride by using modern analytical techniques. For this study, the berberine chloride sample was divided into two parts among which, one part was named as control as no Biofield Energy Treatment was given to it; while the other part received the Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Alice Branton and named as the Biofield Energy Treated sample. The PXRD results revealed some changes in the Bragg’s angle of peaks along with - 7.24% to 188.78% alterations in the peak intensities and -65.88% to 135.42% changes in the crystallite sizes of the treated sample. Also, there was 1.91% decrease in the average crystallite size of the treated sample compared to the control sample. The particle size of the treated sample was significantly reduced by 20.16% (d10), 17.21% (d50), 27.53% (d90), and 27.36% {D(4,3)}; along with 15.31% increase in the specific surface area compared with the control sample. The total weight loss was significantly reduced by 25.81%; however, the residue amount was significantly increased by 55.04% in the treated sample compared to the control sample. Besides, the DSC thermogram showed four peaks, in which the peak temperatures of the treated sample corresponding to 1st, 2nd, 3rd, and 4th peak were altered by -2.26%, 3.55%, - 4.50%, and -0.69%, respectively. Moreover, the latent heat for 1st, 2nd, 3rd, and 4th peak of the treated sample were significantly reduced by 24.04%, 42.44%, 44.26%, and 47.78%, respectively, compared with the control sample. The results showed that the Trivedi Effect®-Consciousness Energy Healing Treatment might help in improving the solubility, absorption, and bioavailability of berberine chloride compared with the control sample. Hence, the Consciousness Energy Healing Treatment would be useful for designing the novel nutraceutical/pharmaceutical formulations of berberinechloride with improved drug profile for the treatment of various microbial diseases and disorders such as diarrhea, gastroenteritis, hypertension, tumor, malaria, hyperglycemia, inflammation, arrhythmia, infections, etc.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131431556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-10-31DOI: 10.5958/2321-5836.2018.00032.0
S. Kadam, S. Chavhan, S. Shinde, P. Sapkal
Datura, a wildly growing plant from Solanaceae family, is attributed with both poisonous and medicinal values. Datura spp. in Ayurveda, different parts of Datura is used for various human ailments when applied both locally and through oral administration. Several functional groups have been reported to be present in different parts of the plant. The plant shows various types of activities such as analgesic, anti-inflammatory, anti-viral, and anti-diarrheal that may be due to the presence of the active chemical constituents. especially in Ayurvedic medicine, D. stramonium has been used for curing various human ailments, including ulcers, wounds, inflammation, rheumatism and gout, sciatica, bruises and swellings, fever, asthma and bronchitis, and toothache. This comprehensive review of D. stramonium includes information on botany, phytochemistry, pharmacology, toxicology and ethnomedicinal uses.
{"title":"Pharmacognostic Review on Datura","authors":"S. Kadam, S. Chavhan, S. Shinde, P. Sapkal","doi":"10.5958/2321-5836.2018.00032.0","DOIUrl":"https://doi.org/10.5958/2321-5836.2018.00032.0","url":null,"abstract":"Datura, a wildly growing plant from Solanaceae family, is attributed with both poisonous and medicinal values. Datura spp. in Ayurveda, different parts of Datura is used for various human ailments when applied both locally and through oral administration. Several functional groups have been reported to be present in different parts of the plant. The plant shows various types of activities such as analgesic, anti-inflammatory, anti-viral, and anti-diarrheal that may be due to the presence of the active chemical constituents. especially in Ayurvedic medicine, D. stramonium has been used for curing various human ailments, including ulcers, wounds, inflammation, rheumatism and gout, sciatica, bruises and swellings, fever, asthma and bronchitis, and toothache. This comprehensive review of D. stramonium includes information on botany, phytochemistry, pharmacology, toxicology and ethnomedicinal uses.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134458398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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