Fluid Mixing Using Induced Charge Electro-Osmotic Transverse Flow Actuated by Asymmetrical Driving Electrode Sequence

Xiaoming Chen, Yukun Ren, Likai Hou, Tianyi Jiang, Hongyuan Jiang
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Abstract

Microfluid mixing is an essential process in chemical analysis, drug test, and nanoparticle synthesis. Induced charge electro-osmosis (ICEO) has good capability in microfluid mixing for its reconfigurable vortex profile. We found experimentally ICEO transverse flow induced by the asymmetrical driving electrode has a good performance in disturbing the interface of two fluids. Encouraged by these aspects, we proposed a micromixer using ICEO transverse flows actuated by the asymmetrical driving electrode sequence to mix microfluids. We established a simulation model to investigate the evolution of the interface and demonstrate the work principle of this method. Moreover, we numerically explored the effects of device structure, and electrolyte characteristics on the capability of micromixer. Finally, we validated this method experimentally, and studied the effects of voltage intensity, frequency and flow rate on the mixing capability, obtaining mixing efficiency exceeding 94%. This method is a potential alternative in various microfluidic and lab-on-a-chip applications.
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非对称驱动电极序列诱导电荷电渗透横向流动混合流体
微流体混合是化学分析、药物试验和纳米颗粒合成的重要过程。感应电荷电渗透(ICEO)因其涡型可重构而具有良好的微流体混合性能。实验结果表明,非对称驱动电极诱导的ICEO横向流动对扰动两种流体的界面有很好的效果。在这些方面的鼓励下,我们提出了一种利用非对称驱动电极序列驱动的ICEO横向流动混合微流体的微混合器。建立了仿真模型,研究了界面的演化过程,验证了该方法的工作原理。此外,我们还通过数值计算探讨了器件结构和电解质特性对微混合器性能的影响。最后,对该方法进行了实验验证,并研究了电压强度、频率和流量对混合能力的影响,得到了超过94%的混合效率。这种方法在各种微流体和芯片实验室应用中是一种潜在的替代方法。
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