Acrokeratosis verruciformis of Hopf: A rare case report

Shushruta Mohanty, Sujata Panda, Deepika Sahu, Shilpa Padhi
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Abstract

Acrokeratosis verruciformis of Hopf (AKV) is a rare cutaneous autosomal dominant genodermatosis described by Hopf in 1931. It usually presents at birth or may appear as late as 5 decade of life. It is characterized by multiple hyperkeratotic, verrucous papules/plaques to multiple planar wart like lesions on dorsal aspects of hand and feet. Due to rarity of the case, we present a case of AKV in a 60-year-old male that was diagnosed on histopathology. We the authors have attempted to describe the histological features of AKV with differential diagnosis of these lesions through review of literature.
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疣状肢端角化病1例
Hopf疣状角化Acrokeratosis of Hopf (AKV)是一种罕见的皮肤常染色体显性遗传病。它通常在出生时出现,也可能在50岁时出现。它的特征是手和脚背部的多个角化过度,疣状丘疹/斑块到多个平面疣样病变。由于罕见的情况下,我们提出一个病例AKV在60岁的男性被诊断为组织病理学。我们的作者已经试图描述AKV的组织学特征与鉴别诊断这些病变通过回顾文献。
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