[Carbon disulfide excretion in urine--a biological exposure test for the workplace and environmental concentration ranges].

H Winkelmann, J Prösch, W Engewald, K Horn
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Abstract

The biological control procedure for carbon disulphide (CS2), the determination of free and bound CS2 in urine--a procedure already applied to hygienic surveillance--were modified by using gas chromatography and sulphide selective detection (FPD). The results obtained by the changed biological monitoring test in workplace and environmental surveillance are present and discussed. For CS2 concentrations at workplaces in the range of 8-54 mg/m3 a correlation coefficient of r = 0.56 (n = 11, p less than 0.07) was calculated for the mathematical connection of CS2 shift exposure and CS2 content in urine. For environmental exposures in the range of the CS2 immision short term threshold value (MIKK) of 0.03 mg/m3 the procedure may discriminate significantly exposure load from naturally occurring CS2 background.

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[尿中二硫化碳排泄——工作场所和环境浓度范围的生物暴露试验]。
二硫化碳(CS2)的生物控制程序,尿液中游离和结合CS2的测定-已经应用于卫生监测的程序-通过使用气相色谱法和硫化物选择性检测(FPD)进行了修改。介绍并讨论了在工作场所和环境监测中进行生物监测试验的结果。对于工作场所CS2浓度在8-54 mg/m3范围内,计算出CS2位移暴露与尿液中CS2含量的数学联系的相关系数r = 0.56 (n = 11, p小于0.07)。对于处于CS2排放短期阈值(MIKK) 0.03 mg/m3范围内的环境暴露,该程序可以显著区分暴露负荷与自然发生的CS2背景。
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