Antimicrobial Activity of Ba-MOF

Abstract

: The increasing tolerance and resistance of pathogens to conventional antibiotics is a global health issue, and there is a need to use effective and new substances. Metal–organic frameworks (MOFs) are highly functional materials with antimicrobial properties that come from their composition, structure, and high internal volume, which could be a source for antimicrobial guest molecules integrated into the pores. In addition, MOFs can contain more than one type of metal ion in the same structure. In this work, a metal–organic framework, [Ba(H 2 btec) · H 2 O] n , was synthesized by the deposition method using benzene-1,2,4,5-tetracarboxylic acid (H4btec) and Ba(NO 3 ) 2 . Characterization of the MOF was performed using Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), Fourier Transform Infrared (FTIR) and x-ray fluorescence (XRF) alyses. The metal–organic framework was used against Gram-positive and Gram-negative bacteria including Keleb peneumonia , Staph coccus aureus , Staph sapropphyticus , and Esherichia coli .