{"title":"Does Chronic Ketone Salt Supplementation Alter BP, CBC, or CMP Results in Adults Diagnosed with PTSD?","authors":"J. Locklin, A. Holland, Andrew Moore","doi":"10.21633/ISSN.2380.5064/S.2021.04.01.22","DOIUrl":null,"url":null,"abstract":"Post-traumatic stress disorder is a condition that is associated with high levels of stress that can be linked to elevated resting blood pressure and heart rates in those who have it. Ketone bodies are chemicals that the body utilizes as fuel when glucose is not readily available, and have been shown to improve metabolic diseases, as well as decrease systolic blood pressure in healthy populations. The purpose of this study was to determine if chronic ketone salt supplementation alters blood pressure (BP), complete blood count (CBC), or comprehensive metabolic panel (CMP) results in adults diagnosed with PTSD. The hypothesis was that 6-weeks of chronic KS consumption will not have any negative effects on the CMP and CBC health markers, and potentially have positive effects on BP in the PTSD population. Participants included males and females between the ages of 2165 years of age, all of whom had been previously diagnosed with post-traumatic stress disorder (PTSD). The study was randomized, double-blinded, and placebo-controlled. The findings of the study showed that there were no significant interactions, positive or negative, between 6-weeks of chronic KS supplementation and BP, CBC, and CMP in adults with PTSD. Received: 01/31/2020 Accepted: 02/17/2020 Correspondence: Jordan Locklin, Augusta University, 1120 15 St. Augusta, GA 30912, jolocklin@augusta.edu","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"31 3 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Arsenal: The Undergraduate Research Journal of Augusta University","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21633/ISSN.2380.5064/S.2021.04.01.22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Post-traumatic stress disorder is a condition that is associated with high levels of stress that can be linked to elevated resting blood pressure and heart rates in those who have it. Ketone bodies are chemicals that the body utilizes as fuel when glucose is not readily available, and have been shown to improve metabolic diseases, as well as decrease systolic blood pressure in healthy populations. The purpose of this study was to determine if chronic ketone salt supplementation alters blood pressure (BP), complete blood count (CBC), or comprehensive metabolic panel (CMP) results in adults diagnosed with PTSD. The hypothesis was that 6-weeks of chronic KS consumption will not have any negative effects on the CMP and CBC health markers, and potentially have positive effects on BP in the PTSD population. Participants included males and females between the ages of 2165 years of age, all of whom had been previously diagnosed with post-traumatic stress disorder (PTSD). The study was randomized, double-blinded, and placebo-controlled. The findings of the study showed that there were no significant interactions, positive or negative, between 6-weeks of chronic KS supplementation and BP, CBC, and CMP in adults with PTSD. Received: 01/31/2020 Accepted: 02/17/2020 Correspondence: Jordan Locklin, Augusta University, 1120 15 St. Augusta, GA 30912, jolocklin@augusta.edu
创伤后应激障碍是一种与高水平压力相关的疾病,可能与患者的静息血压和心率升高有关。酮体是人体在葡萄糖缺乏时用作燃料的化学物质,已被证明可以改善代谢性疾病,并降低健康人群的收缩压。本研究的目的是确定慢性酮盐补充是否会改变诊断为PTSD的成年人的血压(BP)、全血细胞计数(CBC)或综合代谢组(CMP)结果。假设是,6周的慢性KS消费不会对CMP和CBC健康指标产生任何负面影响,并可能对PTSD人群的血压产生积极影响。参与者包括年龄在2165岁之间的男性和女性,他们之前都被诊断患有创伤后应激障碍(PTSD)。该研究采用随机、双盲和安慰剂对照。研究结果显示,6周的慢性KS补充与成年PTSD患者的BP、CBC和CMP之间没有显著的正或负相互作用。收稿日期:2020年01月31日收稿日期:2020年02月17日通讯:Jordan Locklin, Augusta University, 1120 15 St. Augusta, GA 30912, jolocklin@augusta.edu