Pub Date : 2021-05-18DOI: 10.21633/ISSN.2380.5064/S.2021.04.01.22
J. Locklin, A. Holland, Andrew Moore
Post-traumatic stress disorder is a condition that is associated with high levels of stress that can be linked to elevated resting blood pressure and heart rates in those who have it. Ketone bodies are chemicals that the body utilizes as fuel when glucose is not readily available, and have been shown to improve metabolic diseases, as well as decrease systolic blood pressure in healthy populations. The purpose of this study was to determine if chronic ketone salt supplementation alters blood pressure (BP), complete blood count (CBC), or comprehensive metabolic panel (CMP) results in adults diagnosed with PTSD. The hypothesis was that 6-weeks of chronic KS consumption will not have any negative effects on the CMP and CBC health markers, and potentially have positive effects on BP in the PTSD population. Participants included males and females between the ages of 2165 years of age, all of whom had been previously diagnosed with post-traumatic stress disorder (PTSD). The study was randomized, double-blinded, and placebo-controlled. The findings of the study showed that there were no significant interactions, positive or negative, between 6-weeks of chronic KS supplementation and BP, CBC, and CMP in adults with PTSD. Received: 01/31/2020 Accepted: 02/17/2020 Correspondence: Jordan Locklin, Augusta University, 1120 15 St. Augusta, GA 30912, jolocklin@augusta.edu
创伤后应激障碍是一种与高水平压力相关的疾病，可能与患者的静息血压和心率升高有关。酮体是人体在葡萄糖缺乏时用作燃料的化学物质，已被证明可以改善代谢性疾病，并降低健康人群的收缩压。本研究的目的是确定慢性酮盐补充是否会改变诊断为PTSD的成年人的血压(BP)、全血细胞计数(CBC)或综合代谢组(CMP)结果。假设是，6周的慢性KS消费不会对CMP和CBC健康指标产生任何负面影响，并可能对PTSD人群的血压产生积极影响。参与者包括年龄在2165岁之间的男性和女性，他们之前都被诊断患有创伤后应激障碍(PTSD)。该研究采用随机、双盲和安慰剂对照。研究结果显示，6周的慢性KS补充与成年PTSD患者的BP、CBC和CMP之间没有显著的正或负相互作用。收稿日期:2020年01月31日收稿日期:2020年02月17日通讯:Jordan Locklin, Augusta University, 1120 15 St. Augusta, GA 30912, jolocklin@augusta.edu
{"title":"Does Chronic Ketone Salt Supplementation Alter BP, CBC, or CMP Results in Adults Diagnosed with PTSD?","authors":"J. Locklin, A. Holland, Andrew Moore","doi":"10.21633/ISSN.2380.5064/S.2021.04.01.22","DOIUrl":"https://doi.org/10.21633/ISSN.2380.5064/S.2021.04.01.22","url":null,"abstract":"Post-traumatic stress disorder is a condition that is associated with high levels of stress that can be linked to elevated resting blood pressure and heart rates in those who have it. Ketone bodies are chemicals that the body utilizes as fuel when glucose is not readily available, and have been shown to improve metabolic diseases, as well as decrease systolic blood pressure in healthy populations. The purpose of this study was to determine if chronic ketone salt supplementation alters blood pressure (BP), complete blood count (CBC), or comprehensive metabolic panel (CMP) results in adults diagnosed with PTSD. The hypothesis was that 6-weeks of chronic KS consumption will not have any negative effects on the CMP and CBC health markers, and potentially have positive effects on BP in the PTSD population. Participants included males and females between the ages of 2165 years of age, all of whom had been previously diagnosed with post-traumatic stress disorder (PTSD). The study was randomized, double-blinded, and placebo-controlled. The findings of the study showed that there were no significant interactions, positive or negative, between 6-weeks of chronic KS supplementation and BP, CBC, and CMP in adults with PTSD. Received: 01/31/2020 Accepted: 02/17/2020 Correspondence: Jordan Locklin, Augusta University, 1120 15 St. Augusta, GA 30912, jolocklin@augusta.edu","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"31 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132347170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-05DOI: 10.21633/ISSN.2380.5064/S.2020.03.02.33
Emily Archer, James Xie, Alexander White, Edric Leung, Meghann Grenier, Janis Cheng, Lily de Loe, Raymond Ye, Andrew Downie
The search for extant life has long been an interest since people have been able to successfully explore other worlds. However, on space missions, experiments must be performed autonomously, with limited resources, and a carefully selected suite of instruments. Instruments are additionally constrained by weight, reliability, and size which limits use of many modern advanced systems. The Queen’s Space Engineering Team (QSET) is proposing the design of a portable (12” x 12” x 12”) instrument to identify signs supporting extant life aboard a mobile rover platform during exploration missions. The instrument will receive soil samples collected by the rover, analyse the composition to identify key molecules, and transmit data back to a ground station. This system relies on colorimetric measurements using a UV-VIS spectrometer and features a solvent recycle system to minimize weight and waste. This project is part of a larger environment characterisation module to be mounted on a Mars rover system designed for competition at the University Rover Challenge (URC) at the Mars Desert Research Station (MDRS) in Utah. As of this date, each subsystem has successfully passed performance testing and the entire instrument is entering its system-level prototyping stage.
{"title":"The Application of Low-Cost, Close-Range Photogrammetry in Dentistry","authors":"Emily Archer, James Xie, Alexander White, Edric Leung, Meghann Grenier, Janis Cheng, Lily de Loe, Raymond Ye, Andrew Downie","doi":"10.21633/ISSN.2380.5064/S.2020.03.02.33","DOIUrl":"https://doi.org/10.21633/ISSN.2380.5064/S.2020.03.02.33","url":null,"abstract":"The search for extant life has long been an interest since people have been able to successfully explore other worlds. However, on space missions, experiments must be performed autonomously, with limited resources, and a carefully selected suite of instruments. Instruments are additionally constrained by weight, reliability, and size which limits use of many modern advanced systems. The Queen’s Space Engineering Team (QSET) is proposing the design of a portable (12” x 12” x 12”) instrument to identify signs supporting extant life aboard a mobile rover platform during exploration missions. The instrument will receive soil samples collected by the rover, analyse the composition to identify key molecules, and transmit data back to a ground station. This system relies on colorimetric measurements using a UV-VIS spectrometer and features a solvent recycle system to minimize weight and waste. This project is part of a larger environment characterisation module to be mounted on a Mars rover system designed for competition at the University Rover Challenge (URC) at the Mars Desert Research Station (MDRS) in Utah. As of this date, each subsystem has successfully passed performance testing and the entire instrument is entering its system-level prototyping stage.","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121768191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-05DOI: 10.21633/issn.2380.5064/s.2020.03.02.12
E. Geister, R. Esquivel, Danielle Crethers, Danalynn Weatherholt, M. G. Sanchez, Gustavo Munoz
{"title":"Fast-Track Extubation in Infancy and Early Childhood Following Heart Surgery: Outcome Analysis and Predictors of Failure","authors":"E. Geister, R. Esquivel, Danielle Crethers, Danalynn Weatherholt, M. G. Sanchez, Gustavo Munoz","doi":"10.21633/issn.2380.5064/s.2020.03.02.12","DOIUrl":"https://doi.org/10.21633/issn.2380.5064/s.2020.03.02.12","url":null,"abstract":"","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116487313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-05DOI: 10.21633/ISSN.2380.5064/S.2020.03.02.23
James DeBew
{"title":"Ionic and Covalent Conjugates of Metronidazole and Tryptamine","authors":"James DeBew","doi":"10.21633/ISSN.2380.5064/S.2020.03.02.23","DOIUrl":"https://doi.org/10.21633/ISSN.2380.5064/S.2020.03.02.23","url":null,"abstract":"","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116480849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-05DOI: 10.21633/issn.2380.5064/s.2020.03.02.28
S. O'Bryant, Casey Derella, Jeffrey Thomas, J. Looney, Marie-Rose Bieck
Cardiovascular disease (CVD) is the most prominent killer within Type 1 Diabetes (T1D) with endothelial dysfunction as a major player in the development of CVD. Women with T1D experience an accelerated CVD risk despite the apparent sex-specific cardio-protection from circulating endogenous estrogen experienced by heathy pre-menopausal women. Animal models have shown the modulation of SIRT1, a NAD+ histone deacetylase, by estrogen as a CVD protector. This study sought to test the hypothesis that lower circulating SIRT1 is associated with reduced endothelial function in T1D women. Change in flow mediated dilation (FMD), a clinical measure of endothelial function, and SIRT1 over the menstrual cycle exhibited contrasting trends between T1D women and healthy women: increases of FMD and SIRT1 as estrogen increases in healthy women and decreases of FMD and SIRT1 as estrogen increases in T1D women. This provides evidence that signaling roles by circulating estrogen may be attenuated in T1D and that the effects of decreased SIRT1 contributes to endothelial dysfunction, resulting in determinant effects on vascular health in T1D women.
{"title":"Diabetes Attenuation of the Estrogen-Mediated Increase in Endothelial Function is Associated with Circulating SIRT1","authors":"S. O'Bryant, Casey Derella, Jeffrey Thomas, J. Looney, Marie-Rose Bieck","doi":"10.21633/issn.2380.5064/s.2020.03.02.28","DOIUrl":"https://doi.org/10.21633/issn.2380.5064/s.2020.03.02.28","url":null,"abstract":"Cardiovascular disease (CVD) is the most prominent killer within Type 1 Diabetes (T1D) with endothelial dysfunction as a major player in the development of CVD. Women with T1D experience an accelerated CVD risk despite the apparent sex-specific cardio-protection from circulating endogenous estrogen experienced by heathy pre-menopausal women. Animal models have shown the modulation of SIRT1, a NAD+ histone deacetylase, by estrogen as a CVD protector. This study sought to test the hypothesis that lower circulating SIRT1 is associated with reduced endothelial function in T1D women. Change in flow mediated dilation (FMD), a clinical measure of endothelial function, and SIRT1 over the menstrual cycle exhibited contrasting trends between T1D women and healthy women: increases of FMD and SIRT1 as estrogen increases in healthy women and decreases of FMD and SIRT1 as estrogen increases in T1D women. This provides evidence that signaling roles by circulating estrogen may be attenuated in T1D and that the effects of decreased SIRT1 contributes to endothelial dysfunction, resulting in determinant effects on vascular health in T1D women.","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115201121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-04DOI: 10.21633/issn.2380.5064/s.2020.03.02.47
Rachel Visintainer
{"title":"Give Rise","authors":"Rachel Visintainer","doi":"10.21633/issn.2380.5064/s.2020.03.02.47","DOIUrl":"https://doi.org/10.21633/issn.2380.5064/s.2020.03.02.47","url":null,"abstract":"","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"107 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125170376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-04DOI: 10.21633/issn.2380.5064/s.2020.03.02.38
Dalia Saj, Najeah Okashah
Increasing obesity rates have put the American population at higher risk for developing obesity-related medical conditions such as hypertension, heart disease, and diabetes. The hydroxycarboxylic acid (HCA) receptor family is a family of G protein-coupled receptors (GPCRs) that are expressed in adipose tissue and function as metabolic sensors, making them potential pharmaceutical targets in the treatment of obesity and other metabolic disorders. The HCA receptor family consists of the HCA1, HCA2, and HCA3 receptors, which are activated by hydroxycarboxylic acids such as lactate and 3-hydroxybutyric acid. We utilized bioluminescence resonance energy transfer (BRET) to study agonist-induced coupling of luciferase-tagged HCA receptors to Venus fluorescent protein-tagged G protein heterotrimers or arrestins. Our results indicate that the three HCA receptors couple to the Gi/o subfamily of G proteins. The data additionally confirms a lack of coupling to the other G protein subfamilies (Gs, Gq, and G12) and lacks evidence of arrestin recruitment to HCA receptors. Overall, our study highlights the use of BRET as a powerful tool for analysis of GPCR signaling and demonstrates its possible use for future studies to determine the potency of potential drugs targeting HCA receptors as a therapy for health-related problems such as obesity.
{"title":"Investigating Signaling Pathways Involving the HCA Receptor Family","authors":"Dalia Saj, Najeah Okashah","doi":"10.21633/issn.2380.5064/s.2020.03.02.38","DOIUrl":"https://doi.org/10.21633/issn.2380.5064/s.2020.03.02.38","url":null,"abstract":"Increasing obesity rates have put the American population at higher risk for developing obesity-related medical conditions such as hypertension, heart disease, and diabetes. The hydroxycarboxylic acid (HCA) receptor family is a family of G protein-coupled receptors (GPCRs) that are expressed in adipose tissue and function as metabolic sensors, making them potential pharmaceutical targets in the treatment of obesity and other metabolic disorders. The HCA receptor family consists of the HCA1, HCA2, and HCA3 receptors, which are activated by hydroxycarboxylic acids such as lactate and 3-hydroxybutyric acid. We utilized bioluminescence resonance energy transfer (BRET) to study agonist-induced coupling of luciferase-tagged HCA receptors to Venus fluorescent protein-tagged G protein heterotrimers or arrestins. Our results indicate that the three HCA receptors couple to the Gi/o subfamily of G proteins. The data additionally confirms a lack of coupling to the other G protein subfamilies (Gs, Gq, and G12) and lacks evidence of arrestin recruitment to HCA receptors. Overall, our study highlights the use of BRET as a powerful tool for analysis of GPCR signaling and demonstrates its possible use for future studies to determine the potency of potential drugs targeting HCA receptors as a therapy for health-related problems such as obesity.","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116793196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-04DOI: 10.21633/issn.2380.5064/s.2020.03.02.41
Arika Shaikh
Edgar Allan Poe’s “The-Tell Tale Heart” delves into the human psyche as it entails the story of an unnamed narrator who tells the tale of the murder he commits. Undergoing an emotional rollercoaster of pleasure and guilt, Poe’s protagonist maintains his claim to sanity and a sense of reality. Poe articulates many tone and rhythm changes to create a sense of tension, representing the narrator’s mental condition. Throughout the narrative, the narrator struggles to reassure that there is nothing wrong and that he is completely normal. Exploring the themes of madness, guilt, and a false sense of reality, Poe’s narrator suffers from a sense of false narrative, a trait characteristic of schizophrenia. In addition, the narrator demonstrates episodes of delusions, auditory hallucinations, diminished emotional responses, and significant disturbances to his normal routine which all allude to schizophrenia. I will utilize the Diagnostic and Statistical Manual 5 (DSM-5) criteria, literary criticisms, and other publications to show the audience the schizophrenic nature of Poe’s narrator. I will discuss the DSM-5 criteria for schizophrenia and demonstrate how the narrator meets those criteria in several circumstances. Utilizing vivid imagery and a scattered style, Poe explores the mental depths of a man suffering from schizophrenia.
{"title":"Portrayal of Mental Illness in Edgar Allan Poe’s “The Tell-Tale Heart”","authors":"Arika Shaikh","doi":"10.21633/issn.2380.5064/s.2020.03.02.41","DOIUrl":"https://doi.org/10.21633/issn.2380.5064/s.2020.03.02.41","url":null,"abstract":"Edgar Allan Poe’s “The-Tell Tale Heart” delves into the human psyche as it entails the story of an unnamed narrator who tells the tale of the murder he commits. Undergoing an emotional rollercoaster of pleasure and guilt, Poe’s protagonist maintains his claim to sanity and a sense of reality. Poe articulates many tone and rhythm changes to create a sense of tension, representing the narrator’s mental condition. Throughout the narrative, the narrator struggles to reassure that there is nothing wrong and that he is completely normal. Exploring the themes of madness, guilt, and a false sense of reality, Poe’s narrator suffers from a sense of false narrative, a trait characteristic of schizophrenia. In addition, the narrator demonstrates episodes of delusions, auditory hallucinations, diminished emotional responses, and significant disturbances to his normal routine which all allude to schizophrenia. I will utilize the Diagnostic and Statistical Manual 5 (DSM-5) criteria, literary criticisms, and other publications to show the audience the schizophrenic nature of Poe’s narrator. I will discuss the DSM-5 criteria for schizophrenia and demonstrate how the narrator meets those criteria in several circumstances. Utilizing vivid imagery and a scattered style, Poe explores the mental depths of a man suffering from schizophrenia.","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125854419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-04DOI: 10.21633/issn.2380.5064/s.2020.03.02.42
Keturah Stewart
{"title":"The Spaces They Occupied: Women as the Determiners of Success in the French Revolution","authors":"Keturah Stewart","doi":"10.21633/issn.2380.5064/s.2020.03.02.42","DOIUrl":"https://doi.org/10.21633/issn.2380.5064/s.2020.03.02.42","url":null,"abstract":"","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117294329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-04DOI: 10.21633/issn.2380.5064/s.2020.03.02.44
Eyana Thomas, Eric Lian, Kimberly Roberts
Patients with diabetes are two to four times more likely to die from cardiac diseases than those without this diagnosis. Cardiac rehabilitation (CR) is known to improve the physical functioning and reduce risk factors in cardiac patients with diabetes. The aim of this study is to evaluate if cardiac patients with comorbidity of diabetes had improved physical functioning (measured by six-minute walk test [6MWT]) and reduced risk factors (measured reduced fasting blood sugar, lipid profile, overweight, fat composition) after the cardiac rehabilitation program. A retrospective observational cohort longitudinal study using secondary data from electronic medical records was conducted. Clinical data were collected from the individual cardiac treatment plan form used by a cardiac rehabilitation center. Among 93 patients, improvement in physical functioning (i.e.: six-minute walk distance) was significant (p-value = <.01). This was done by comparing pre and post 6MWT scores.
{"title":"The Impact of Cardiac Rehabilitation on CVD Risk Factors in Diabetic Patients","authors":"Eyana Thomas, Eric Lian, Kimberly Roberts","doi":"10.21633/issn.2380.5064/s.2020.03.02.44","DOIUrl":"https://doi.org/10.21633/issn.2380.5064/s.2020.03.02.44","url":null,"abstract":"Patients with diabetes are two to four times more likely to die from cardiac diseases than those without this diagnosis. Cardiac rehabilitation (CR) is known to improve the physical functioning and reduce risk factors in cardiac patients with diabetes. The aim of this study is to evaluate if cardiac patients with comorbidity of diabetes had improved physical functioning (measured by six-minute walk test [6MWT]) and reduced risk factors (measured reduced fasting blood sugar, lipid profile, overweight, fat composition) after the cardiac rehabilitation program. A retrospective observational cohort longitudinal study using secondary data from electronic medical records was conducted. Clinical data were collected from the individual cardiac treatment plan form used by a cardiac rehabilitation center. Among 93 patients, improvement in physical functioning (i.e.: six-minute walk distance) was significant (p-value = <.01). This was done by comparing pre and post 6MWT scores.","PeriodicalId":410927,"journal":{"name":"The Arsenal: The Undergraduate Research Journal of Augusta University","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127062635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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