Importance sampling in PET collimator simulations

R. Harrison, S. Dhavala, P.N. Kumar, Y. Shao, T. Lewellen
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Abstract

SimSET (a Simulation System for Emission Tomography) incorporates importance sampling (IS) to accelerate emission tomography simulations. To this point IS has been used in the object being imaged, but not in the collimator. This is an effective strategy for simulations using geometric or perfect-absorber collimators, but breaks down when more realistic collimators are simulated. We are improving the efficiency of collimator simulation with algorithms that complement the IS algorithms used in the object. Recent improvements to the IS in the object have led to many more photons passing through the collimator without intersecting the septa. However, the photons that do intersect septa have much higher weights, resulting in poor quality factors if they are detected. The collimator IS algorithms force these high-weight photons either to penetrate the septa or to scatter toward the detector and then penetrate the septa. This reduces the weights of the photons, improve detection efficiency, and raise the quality factor. The new algorithms are currently focused on collimators for position emission tomography (PET), but the underlying techniques are more broadly applicable.
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PET准直器模拟中的重要采样
SimSET(发射层析成像仿真系统)采用重要性采样(IS)来加速发射层析成像仿真。到目前为止,IS已经在被成像的对象中使用,但没有在准直器中使用。对于使用几何或完全吸收准直器的模拟,这是一种有效的策略,但当模拟更现实的准直器时,这种策略就失效了。我们正在通过补充对象中使用的IS算法的算法来提高准直器仿真的效率。最近对物体中IS的改进导致更多的光子通过准直器而不与隔层相交。然而,与隔层相交的光子具有更高的权重,如果它们被检测到,则导致质量因子较差。准直仪IS算法迫使这些高质量光子要么穿透隔层,要么向探测器散射,然后穿透隔层。这减少了光子的重量,提高了检测效率,提高了质量因子。新的算法目前集中在准直器的位置发射断层扫描(PET),但基础技术更广泛地适用。
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