Simulation of A Bidirectional Microfluidic Pump Actuated by Ultrasound Based on Microcantilever Arrays

Dongyang Chen, Lican Zheng, Jincheng Wang, Yu Xie, Wei Zhou, Tao Luo
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Abstract

In this work, we propose a novel design of a microfluidic pump that can pump flow bidirectionally by changing the frequency of the external remote ultrasound. Finite element analysis (FEA) is used to analyze the feasibility of our design. The bidirectional microfluidic pumping fundamentally relies on the utilization of microcantilevers with different dimensions for achieving distinct resonance frequencies. In this way, ultrasound with different frequencies can be used to induce bidirectional acoustic streaming flow in the microchannel by selective actuation of two microcantilever arrays. The simulation presented in this work shows that the direction of pumping flow can be changed by changing the frequency of the ultrasound, which lays a strong foundation for us to develop an fully implantable bidirectional micropump for applications such as implantable drug delivery and biopsy.
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基于微悬臂阵列的超声驱动双向微流控泵仿真
在这项工作中,我们提出了一种新的微流体泵的设计,可以通过改变外部远程超声的频率来双向泵送流动。采用有限元分析(FEA)对设计的可行性进行了分析。双向微流控泵送从根本上依赖于利用不同尺寸的微悬臂梁来实现不同的共振频率。这样,不同频率的超声可以通过选择性驱动两个微悬臂阵列来诱导微通道内的双向声流流动。本研究的模拟结果表明,通过改变超声频率可以改变泵送流的方向,这为我们开发一种完全可植入的双向微泵,用于植入式药物输送和活检等应用奠定了坚实的基础。
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