Plasmids: Cause of Bacterial Diversity

I-ling Ko
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Abstract

Plasmids, that is, extrachromosomal DNA, were first recognized in Enterobacteriaceae. From that point onward, they were found in practically every one of the strains noticed. The plasmid structure is made out of roundabout twofold abandoned DNA atoms that self-governingly recreate in the host cell. Its length can differ from a couple to many kilobases (kb). In microorganisms, plasmids are moved chiefly on a level plane through the formation cycle. The plasmid replication interaction can be isolated into three phases: inception, expansion and end. The interaction includes DNA helicase I, DNA gyrase, DNA polymerase III, endonuclease and ligase. The plasmid contains qualities fundamental for the capacity of the plasmid and its conservation in the host cell (commencement and control of replication). Some of them have qualities that control the steadiness of the plasmid. Notwithstanding, microorganisms have numerous organic capacities identified with plasmids. The recognizable proof and order of plasmids depend on their lasting hereditary qualities in all plasmids. They are: the capacity to protect themselves and control the replication cycle in the host cell. Along these lines, the plasmid order between the contradictory gatherings is done. The replicon composing technique dependent on genotype instead of phenotypic qualities has similar outcomes as jumble bunching
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质粒:细菌多样性的原因
质粒,即染色体外DNA,最早是在肠杆菌科中发现的。从那时起,几乎在每一种被注意到的菌株中都发现了它们。质粒结构是由在宿主细胞中自动再生的双重废弃DNA原子组成的。它的长度可以从几个千碱基到许多千碱基不等。在微生物中,质粒在形成周期中主要在一个水平平面上移动。质粒复制相互作用可分为起始、扩增和结束三个阶段。相互作用包括DNA解旋酶I、DNA旋合酶、DNA聚合酶III、核酸内切酶和连接酶。质粒包含了质粒在宿主细胞中的容量及其保存(开始和控制复制)的基本性质。其中一些具有控制质粒稳定性的特性。尽管如此,微生物具有许多与质粒鉴定的有机能力。质粒的可识别性和顺序取决于它们在所有质粒中持久的遗传特性。它们是:自我保护和控制宿主细胞复制周期的能力。沿着这条线,质粒在矛盾聚集之间的顺序就完成了。依赖基因型而非表型质量的复制子组合技术与混杂聚束的结果相似
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