Preliminary study of quantitative X-ray spectral imaging with spectral deconvolution

Sen Wang, Li Zhang, Xiaofei Xu, Dufan Wu
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Abstract

The degrading factors of photon counting detectors such as charge-sharing, K-escape, resulting in spectrum distortion, set the crucial limitation for its application in quantitative imaging. We present a method to eliminate the degrading factors by spectral deconvolution. Simulation study and experimental study were carried out to verify its effectiveness and robustness. In simulation study, the method can significantly reduce the bias between detected photon counts and the theoretical value, which implies the effectiveness. Poisson noise was added to test the robustness and we find the result shows no significant difference to noiseless result when up to 106 photons are detected. In experimental study, theoretical spectrum is not easily accessible, instead we verified the effectiveness by calculating the width of an aluminum plate based on Beer-Lambert Law, which is supposed to be consistent among the whole energy range. An improvement can be seen after deconvolution and the output shows a good agreement with simulation result. Furthermore, we simulated a CT reconstruction process using the proposed method and found the reconstructed μ fits the theoretical value very well, which manifests a promising potential in quantitative X-ray spectral imaging.
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光谱反褶积定量x射线光谱成像的初步研究
光子计数探测器的电荷共享、k逃逸等退化因素导致的光谱畸变是限制其在定量成像中的应用的关键因素。提出了一种利用光谱反褶积消除退化因素的方法。仿真研究和实验研究验证了该方法的有效性和鲁棒性。仿真研究表明,该方法能显著减小探测光子数与理论值之间的偏差,证明了该方法的有效性。加入泊松噪声来检验鲁棒性,当检测到106个光子时,结果与无噪声结果没有显著差异。在实验研究中,理论谱不容易获得,我们通过基于Beer-Lambert定律计算铝板的宽度来验证其有效性,该宽度在整个能量范围内应该是一致的。反卷积后的输出与仿真结果吻合较好。利用该方法模拟了CT的重建过程,结果表明重建的μ值与理论值吻合较好,在定量x射线光谱成像中具有广阔的应用前景。
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