The anodic aluminum oxide (AAO) template fabricated Localized Surface Plasmon Resonance (LSPR) sensor for the plasmonic coupling effect study

Chia-Chin Hsieh, Wang-Jiun Lee, Kuan-Chun Yeh, N. Huang
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Abstract

The localized surface plasmon resonance (LSPR) sensing has drawn significant attention in biosensing fields due to its label-free, dynamic, sensitive, and ease-of-operation sensing capability. In our study, we utilized an anodic aluminum oxide (AAO) template to fabricate a large-area LSPR sensor with adjustable nanostructure parameters such as period and diameter. By using different nanostructure patterns, we investigated the plasmonic coupling effect and optimized the nanostructure geometry. Our research demonstrates the real-time and multipoint detection of pathogen DNA sequences. Based on the above features, we believe that this platform has the potential for point-of-care (POC) biosensing applications.
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采用阳极氧化铝(AAO)模板制备局部表面等离子体共振(LSPR)传感器,研究等离子体耦合效应
局部表面等离子体共振(LSPR)传感技术以其无标记、动态、灵敏、易操作等特点在生物传感领域受到广泛关注。在我们的研究中,我们利用阳极氧化铝(AAO)模板制作了一个具有可调节纳米结构参数(如周期和直径)的大面积LSPR传感器。采用不同的纳米结构模式,研究了等离子体耦合效应,优化了纳米结构的几何形状。我们的研究展示了病原体DNA序列的实时和多点检测。基于上述特点,我们认为该平台具有点护理(POC)生物传感应用的潜力。
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