Analysis of the Influence of Nifedipine + Magnesium Sulfate Therapy on the Clinical Effect of Pregnancy-Induced Hypertension, Renal Function, and Pregnancy Outcome

Abstract

Objective: To investigate the effect of nifedipine + magnesium sulfate treatment on pregnancy-induced hypertension. Methods: From January 2020 to January 2023, 60 patients with pregnancy-induced hypertension in our hospital were randomly divided into the control group and the observation group (30 cases in each group). The control group was treated with magnesium sulfate, while the observation group was treated with nifedipine and magnesium sulfate, and the clinical efficacy of the two groups was compared. The effective rate of treatment, blood pressure indicators, renal function indicators, adverse pregnancy outcomes, and quality-of-life scores were investigated. Results: The effective rate of treatment and quality-of-life score in the observation group were higher than those in the control group (P < 0.05). On the other hand, the diastolic and systolic blood pressure, the 24 h urine creatinine and albumin, as well as the adverse pregnancy outcomes were found to be lower in the observation group as compared to the control group (P < 0.05). Conclusion: For patients with pregnancy-induced hypertension, treatment with nifedipine and magnesium sulfate can achieve significant curative and remarkable effects. While improving blood pressure, it can also improve renal function, optimize pregnancy outcomes, and improve quality of life.