Environmental Factors Associated With Sarcopenia : A Systematic Review

Thinakaran Kandayah, Nazarudin Safian, Shamsul Azhar Shah
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Abstract

Introduction: Elderly is a vulnerable population that is prone to sarcopenia which is associated with the loss of muscle mass, strength and function which are some of the diseases that affect the elderly. The association between environmental factors with sarcopenia should be explored as it has the potential to influence the health and disability of a person. At present, limited research is conducted to investigate the association that could be attributed to the complex interaction between human and environmental interactions. Hence this review is conducted to identify the environmental factors associated with sarcopenia. Methods: A systematic review was conducted using PubMed, SCOPUS, Web of Science and manual search following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. We used articles that had been written in English and relevant articles were then screened, duplicates were removed, eligibility criteria were applied, and studies that met the criteria were reviewed. The keywords environmental factors, pollutants food environment, neighbourhood environment, locality and sarcopenia were included. Results: Initial search generated 934 publications and 12 articles were included after the inclusion and exclusion criteria for this review. In this review, environmental factors associated with sarcopenia are divided into 3 themes that comprises of food environment (availability and physical access, economic access and food quality and safety), neighbourhood environment and pollutants. Conclusion: This systematic review revealed an association between the food environment, neighbourhood environment and pollutants with sarcopenia. The findings are salient as they could aid policymakers in formulating the necessary strategy to reduce the morbidity and mortality associated with sarcopenia, especially with the increase in the ageing population globally. Keywords: Environmental factors - elderly - sarcopenia
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与肌肉减少症相关的环境因素:一项系统综述
老年人是一个易受伤害的人群,容易发生肌肉减少症,肌肉减少症与肌肉质量、力量和功能的丧失有关,这是一些影响老年人的疾病。环境因素与肌肉减少症之间的关系应加以探讨,因为它有可能影响一个人的健康和残疾。目前,对人类与环境相互作用之间复杂相互作用的关联进行的研究有限。因此,本综述旨在确定与肌肉减少症相关的环境因素。方法:采用PubMed、SCOPUS、Web of Science和人工检索,按照系统评价和元分析首选报告项目(PRISMA)标准进行系统评价。我们使用了用英语撰写的文章,然后筛选相关文章,删除重复的文章,应用资格标准,并对符合标准的研究进行审查。关键词:环境因素、污染物、食品环境、邻里环境、地域性、肌肉减少症。结果:初步检索产生934篇出版物,按照本综述的纳入和排除标准纳入了12篇文章。本文将与骨骼肌减少症相关的环境因素分为3个主题,包括食品环境(可获得性和物质可及性、经济可及性和食品质量与安全)、邻里环境和污染物。结论:本系统综述揭示了食物环境、邻里环境和污染物与肌肉减少症的关系。这些发现是显著的,因为它们可以帮助决策者制定必要的战略,以减少与肌肉减少症相关的发病率和死亡率,特别是在全球老龄化人口增加的情况下。关键词:环境因素;老年人;肌肉减少症
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