Remineralizing gel with calcium lactate for the prevention of caries in children

E. V. Brusnitsyna, E. S. Ioschenko, I. V. Gavrilov, T. V. Zakirov, L. A. Kaminskaya, N. V. Ozhgikhina, E. S. Bimbas
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Abstract

The article presents the results of a single-center open clinical trial of the use of the remineralizing gel «PRESIDENT Minerals gel 0+». The effectiveness of the drug in children in the period of mixed dentition with a compensated form of caries was studied. Materials and methods . The study involved 19 children, mean age 8,3 years. The duration of the study is 1 month.Clinical indices and laboratory parameters were determined: DMF+df, OHI-S, PMA, the degree of enamel electrometry, calcium, glucose, total protein and antioxidant activity of saliva (AOA). Organoleptic properties were determined on a 5-point scale. Results . After one month of using the remineralizing gel, a decrease in the hygiene index by 23,27%, a decrease in the electrometric evaluation of enamel by 15,58% were revealed. In saliva, a decrease in the level of protein by 33,13% and an increase in the content of calcium by 53,33% were revealed. The organoleptic properties of the gel were evaluated on a five-point scale at 4,31±0,22 points. Conclusion . «PRESIDENT 0+ Minerals gel» with calcium lactate and hydroxyapatite has a remineralizing effect, good organoleptic properties and can be recommended for caries prevention in children.
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乳酸钙再矿化凝胶预防儿童龋齿
文章介绍了使用再矿化凝胶«总统矿物凝胶0+»的单中心开放临床试验的结果。研究了该药在儿童混合牙列补偿性龋齿期的疗效。材料和方法。这项研究涉及19名儿童,平均年龄为8.3岁。研究时间为1个月。测定临床指标及实验室参数:DMF+df、OHI-S、PMA、牙釉质电测度、钙、葡萄糖、总蛋白、唾液抗氧化活性(AOA)。感官特性以5分制确定。结果。使用再矿化凝胶1个月后,牙釉质的卫生指数下降了23.27%,电测评价下降了15.58%。在唾液中,蛋白质水平下降了33.13%,钙含量增加了53.33%。以4.31±0.22分的五分制评价凝胶的感官特性。结论。含有乳酸钙和羟基磷灰石的“总统0+矿物质凝胶”具有再矿化作用,良好的感官特性,可推荐用于儿童龋齿预防。
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