A Comparative Study of Serum Lipid Profile in Normal Pregnancy and Pregnancy Induced Hypertension

Indian Journal of Public Health Research and Development Pub Date : 2023-01-01 DOI:10.37506/ijphrd.v14i4.19782

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Abstract

Background: Pregnancy induced hypertension is a significant contributor to maternal and foetal morbidity andmortality worldwide. Studying the lipid profile and risk variables is crucial for illness prevention, management,and a better prognosis.Method and Materials: This study was a case control study conducted in the Department of Obstetrics andGynaecology, Tezpur Medical College and Hospital, Tezpur. A total of 100 (one hundred) were selected, out ofwhich 50 (fifty) normotensive pregnant women served as a control and 50 (fifty) hypertensive women constitutedthe study group. Besides baseline routine investigations, estimation of Serum lipid profile was done by collectingblood samples from antecubital vein of every case and control and were analysed at department of Biochemistry,Tezpur Medical College and Hospital, Tezpur.Results: The hypertensive group had a significant rise in Triglyceride (TG), total cholesterol, LDL-C levels anddecreased HDL-C levels as compared to the control group.Conclusion: Abnormal lipid profile during pregnancy plays an important role in development of pre-eclampsia.

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正常妊娠与妊娠高血压患者血脂水平的比较研究

背景:妊娠高血压是全世界孕产妇和胎儿发病率和死亡率的重要因素。研究血脂和风险变量对疾病预防、管理和更好的预后至关重要。方法与材料:本研究为病例对照研究，在提斯浦尔医学院妇产科进行。共选取100例，其中50例血压正常的孕妇为对照组，50例高血压妇女为研究组。除了基线常规调查外，还通过从每个病例和对照组的肘部静脉采集血液样本来估计血清脂质谱，并在提斯浦尔医学院和医院生物化学系进行分析。结果:与对照组相比，高血压组甘油三酯(TG)、总胆固醇、LDL-C水平显著升高，HDL-C水平显著降低。结论:妊娠期血脂异常在子痫前期发生发展中起重要作用。

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Indian Journal of Public Health Research and Development

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