Prognostic Biochemical Markers Predicting Severity Caused by COVID 19: A Retrospective Observational Study Conducted in a Small Health-care Set UP in Western U.P.
{"title":"Prognostic Biochemical Markers Predicting Severity Caused by COVID 19: A Retrospective Observational Study Conducted in a Small Health-care Set UP in Western U.P.","authors":"","doi":"10.37506/ijphrd.v14i4.19785","DOIUrl":null,"url":null,"abstract":"Background: For assessment of mild to severe outcome points of SARS COV-2 we need to observe patients withcomorbidities along with basic laboratory markers like NLR, PLR, CRP, D-dimer, serum Ferritin etc. For theprediction of SARS COV-2 severity our study aims at basic available laboratory prognostic biomarkers.Methods and Result: Our study included 46 patients with mild, moderate and severe outcomes which werecategorised according to CRP, Serum Ferritin and D- dimer with p-Value < 0.001 for both outcomes which aresignificant as compared to outcome patients with p-Value = 0.01 which is slightly less significant.Conclusion: A raised value of CRP, ferritin, D-dimer and involvement of male gender and old age patients wereassociated with severity of the disease.Among these parameters, D-dimer was known to be the best predictor of the outcome.","PeriodicalId":13368,"journal":{"name":"Indian Journal of Public Health Research and Development","volume":"27 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Public Health Research and Development","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37506/ijphrd.v14i4.19785","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: For assessment of mild to severe outcome points of SARS COV-2 we need to observe patients withcomorbidities along with basic laboratory markers like NLR, PLR, CRP, D-dimer, serum Ferritin etc. For theprediction of SARS COV-2 severity our study aims at basic available laboratory prognostic biomarkers.Methods and Result: Our study included 46 patients with mild, moderate and severe outcomes which werecategorised according to CRP, Serum Ferritin and D- dimer with p-Value < 0.001 for both outcomes which aresignificant as compared to outcome patients with p-Value = 0.01 which is slightly less significant.Conclusion: A raised value of CRP, ferritin, D-dimer and involvement of male gender and old age patients wereassociated with severity of the disease.Among these parameters, D-dimer was known to be the best predictor of the outcome.