Prognostic Biochemical Markers Predicting Severity Caused by COVID 19: A Retrospective Observational Study Conducted in a Small Health-care Set UP in Western U.P.

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Abstract

Background: For assessment of mild to severe outcome points of SARS COV-2 we need to observe patients withcomorbidities along with basic laboratory markers like NLR, PLR, CRP, D-dimer, serum Ferritin etc. For theprediction of SARS COV-2 severity our study aims at basic available laboratory prognostic biomarkers.Methods and Result: Our study included 46 patients with mild, moderate and severe outcomes which werecategorised according to CRP, Serum Ferritin and D- dimer with p-Value < 0.001 for both outcomes which aresignificant as compared to outcome patients with p-Value = 0.01 which is slightly less significant.Conclusion: A raised value of CRP, ferritin, D-dimer and involvement of male gender and old age patients wereassociated with severity of the disease.Among these parameters, D-dimer was known to be the best predictor of the outcome.
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预测COVID - 19严重程度的预后生化指标:在美国西部一家小型医疗机构进行的回顾性观察研究
背景:为评估SARS - COV-2轻至重度转归点,需观察患者的合并症及NLR、PLR、CRP、d -二聚体、血清铁蛋白等基本实验室指标。对于SARS COV-2严重程度的预测,我们的研究旨在基本可用的实验室预后生物标志物。方法与结果:我们的研究纳入了46例轻、中、重度预后的患者,根据CRP、血清铁蛋白和D-二聚体的p值和p值进行分类;两种结果均为0.001,与p值= 0.01的结果患者相比,p值= 0.01的结果患者的显著性略低。结论:CRP、铁蛋白、d -二聚体的升高及男性、老年患者的参与与疾病的严重程度有关。在这些参数中,已知d -二聚体是结果的最佳预测因子。
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