Effects of aqueous and ethanolic seed extract of Asparagus racemosus Linn on neurobehavioral pattern of acrylamide induced experimental Zebra fish

Abstract

A neuropsychological assessment is a test that assesses how well a person's brain functions. Literacy, language use, attention, learning, processing speed, reasoning, memory, problem-solving, personality and other talents are all assessed. The purpose of this study is to assess the effects of aqueous and ethanolic seed extracts of Asparagus racemosus Linn on the neurobehavioral pattern of acrylamide-induced experimental Zebra fish. In the novel tank test, the number of top entries, top remain time, top entry latency and total distance traveled were all greater in the Asparagus racemosus Linn seed extract group than in the acrylamide group, while the number of bottom entries and bottom duration of stay were lower. In the light-dark test, group II Zebrafish treated with 0.75 mM acrylamide showed anxiety by spending less time in the light zone. In our study, Zebrafish pre-treated with aqueous and ethanolic seed extracts of different concentrations of Asparagus racemosus Linn significantly reversed. In the open field test, the Asparagus racemosus Linn seed extract at different doses significantly improved outer zone (s) and inner zone (S) times compared to the acrylamide control group. In the Y-maze test, the Asparagus racemosus Linn seed extract at different dosages exhibited a dose-influenced significant improvement in the number of entry points to new arms and the total distance walked in the maze in comparison to the acrylamide control group. When compared to the acrylamide control, the Asparagus racemosus Linn seeds extract at various doses demonstrated a significant rise in the amount of time spent in the new arm.