A case of vaccine associated paralytic poliomyelitis in an immune competent child in Morocco

Sanae Lemrabet, Abdelkarim Filali-Maltouf, Leila Medraoui, Hicham Oumzil
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Abstract

This article describes the case of a previously healthy immune-competent child who, despite having received full protection against poliomyelitis with OPV, developed severe flaccid paralysis which eventually led to his death. Poliovirus testing of his contacts revealed the presence of Sabin-like type 3 poliovirus in one of them. The patient developed paralysis and respiratory distress and deceased a few months after the onset of paralysis with respiratory failure. This tragic case report demonstrates the emergence of VAPP and emphasizes the significance of early diagnosis of VAPP infections to enhance the clinical management of VAPP-infected patients.
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摩洛哥一名免疫能力儿童发生疫苗相关麻痹性脊髓灰质炎病例
这篇文章描述了一个以前健康的免疫能力儿童的病例,尽管接种了口服脊髓灰质炎疫苗,得到了预防脊髓灰质炎的充分保护,但他患上了严重的弛缓性麻痹,最终导致他死亡。对其接触者进行的脊髓灰质炎病毒检测显示,其中一人体内存在萨宾样3型脊髓灰质炎病毒。患者出现麻痹和呼吸窘迫,在麻痹并呼吸衰竭发作几个月后死亡。这一悲剧性病例报告证明了VAPP的出现,并强调了VAPP感染的早期诊断对加强VAPP感染患者的临床管理的意义。
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