{"title":"Formulation of nano spray preparation from Purslane Leaf Extract (Portulaca\n oleracea l.) as sunscreen","authors":"Elmiawati Latifah","doi":"10.55522/jmpas.v13i1.5890","DOIUrl":null,"url":null,"abstract":"Purslane plant (Portulaca oleracea L.) is a type of wild plant that grows\n abundantly, but its benefits are rarely known. Purslane contains saponins, which have\n high antioxidant and biological activity. Skin that is sensitive to sun exposure is the\n issue this nanospray is targeting. The aim of this research is to determine the optimal\n formulation of herbal nanospray products with Purslane sunscreen to treat skin problems\n caused by sun exposure. The research method used was an experimental method with\n research stages starting from plant determination, extract making, nanospray formulation\n determination, preparation evaluation, in vivo UV protection activity test, and in vitro\n SPF test. Quantitative descriptive analysis was carried out using Microsoft Excel and\n SPSS Version 24. There were significant differences in erythema (lesions on the skin)\n between the 4 treatment groups, with significant differences in the negative control and\n positive control groups, as well as the group given dose treatment (the amount of\n extract in the nanoparticles) of 0.8 g and 0.4 g of purslane extract with the negative\n control. So, it can be concluded that doses of 0.8 g (SPF value: 9.9) and 0.4 g (SPF\n value: 8.43) of purslane extract have the potential to be sunscreens with maximum\n category and extra protective power. Purslane extract nanospray sunscreen has the\n advantage of being made from herbal ingredients, which have less potential for\n irritation than chemical sunscreen products.","PeriodicalId":16445,"journal":{"name":"Journal of Medical pharmaceutical and allied sciences","volume":"19 9","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical pharmaceutical and allied sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55522/jmpas.v13i1.5890","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Purslane plant (Portulaca oleracea L.) is a type of wild plant that grows
abundantly, but its benefits are rarely known. Purslane contains saponins, which have
high antioxidant and biological activity. Skin that is sensitive to sun exposure is the
issue this nanospray is targeting. The aim of this research is to determine the optimal
formulation of herbal nanospray products with Purslane sunscreen to treat skin problems
caused by sun exposure. The research method used was an experimental method with
research stages starting from plant determination, extract making, nanospray formulation
determination, preparation evaluation, in vivo UV protection activity test, and in vitro
SPF test. Quantitative descriptive analysis was carried out using Microsoft Excel and
SPSS Version 24. There were significant differences in erythema (lesions on the skin)
between the 4 treatment groups, with significant differences in the negative control and
positive control groups, as well as the group given dose treatment (the amount of
extract in the nanoparticles) of 0.8 g and 0.4 g of purslane extract with the negative
control. So, it can be concluded that doses of 0.8 g (SPF value: 9.9) and 0.4 g (SPF
value: 8.43) of purslane extract have the potential to be sunscreens with maximum
category and extra protective power. Purslane extract nanospray sunscreen has the
advantage of being made from herbal ingredients, which have less potential for
irritation than chemical sunscreen products.