Collapsing glomerulopathy; a review on current studies

Azar Baradaran, Padideh Daneii, Mahshid Imankhan, Mahsa Motieian, Sina Neshat
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Abstract

Collapsing glomerulopathy is a rare and serious disease that is characterized by a rapid deterioration of kidney function and heavy proteinuria. This disease is a variant of focal segmental glomerulosclerosis (FSGS). The disease is more serious than other types of FSGS, with high risks of renal failure and poor prognosis. Collapsing glomerulopathy is often resistant to immunosuppressive therapy and can rapidly result in renal failure, making diagnosing and managing this disease an enormous challenge.
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glomerulopathy崩溃;当前研究综述
塌陷性肾小球病是一种罕见而严重的疾病,其特点是肾功能迅速恶化和大量蛋白尿。此病是局灶节段性肾小球硬化(FSGS)的一种变体。该病较其他类型的FSGS更为严重,肾功能衰竭风险高,预后差。塌缩性肾小球病通常对免疫抑制治疗具有耐药性,并可迅速导致肾功能衰竭,这使得诊断和治疗这种疾病成为一项巨大的挑战。
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