Pharmacological Treasures of the Moraceae Family: Bioactive Compounds and Therapeutic Potential

Abstract

The Moraceae family, comprising 50 genera and around 1,400 species thriving in tropical and subtropical regions globally, holds profound botanical significance. Esteemed for its medicinal attributes, this review presents a comprehensive synthesis of the family's bioactive constituents, traditional applications, and pharmaceutical potential. Within the phytochemical realm, Moraceae plants offer a rich array of active agents, including flavonoids, alkaloids, glycosides, saponins, tannins, phytoalexins (such as chalcomoracin), anthocyanins, and glycoproteins, with promising pharmacological potential. Pharmacologically, the review reveals a wide spectrum of effects, including antioxidant, hypoglycemic, anticancer, hepatoprotective, anthelmintic, antihypertensive, and antimicrobial properties. Drawing from an exhaustive literature analysis and in-depth study of Moraceae's bioactivity and phytochemical composition, along with exploration of its traditional uses and pharmacological effects, this discourse aims to guide future researchers. With herbal products' substantial potential, this review serves as a valuable resource for advancing botanical medicine research.