Toward A New Paradigm of Genomics Research

Zhang Zhang, Songnian Hu, Jun Yu
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Abstract

Twenty years after the completion and forty years after the proposal of the Human Genome Project (HGP), genomics, together with its twin field – bioinformatics, has entered a new paradigm, where its bioscience-related, discipline-centric applications have been creating many new research frontiers. Beijing Institute of Genomics (BIG) and now also known as China National Center for Bioinformation (CNCB), will play key roles in supporting and participating in these frontier research activities. On the 20th anniversary of the establishment of BIG, we provide a brief retrospective of its historic events and ascertain strategic research directions with a broader vision for future genomics, where digital genome, digital medicine, and digital health are so structured to meet the needs of human life and healthcare, as well as their related metaverses.
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迈向基因组学研究的新范式
在人类基因组计划(HGP)完成和提出四十年后,基因组学及其孪生领域-生物信息学已经进入了一个新的范式,其与生物科学相关的、以学科为中心的应用已经创造了许多新的研究前沿。北京基因组研究所(BIG),即现在的中国国家生物信息中心(CNCB),将在支持和参与这些前沿研究活动中发挥关键作用。在BIG成立20周年之际,我们简要回顾了其历史事件,并以更广阔的视野确定了未来基因组学的战略研究方向,数字基因组、数字医学和数字健康是如此结构化,以满足人类生活和医疗保健的需求,以及它们相关的meta。
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