Trend and Epidemiology of Tetanus in Nasarawa State, Nigeria: A Five Years Review

Hassan Ikrama Ibrahim, Bello Surajudeen Oyeleke, Odonye Caleb Eselema, Lawal Abdulmumuni, Audu Esther Solomon, Anazodo Michael Chidi
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Abstract

Background: Tetanus is a vaccine preventable, non-communicable disease known as lockjaw and characterized by muscle spasm. It is a forgotten disease in the developed world but remained an infection of public health importance in the developing countries. This study aimed to determine the trend in its epidemiology and outcome in Nasarawa state. Subjects and Method: A retrospective study using secondary data from the medical records of three selected health facilities, one each across the three senatorial zones of the state. All those who had tetanus were included while those with incomplete records, 5 were excluded. Data analysis was done using a statistical package for social sciences version 23. The dependent variable was the outcome of tetanus while the independent variables were incubation period, onset period, type of tetanus, risk factors, vaccination history, and manifestations of tetanus. Results: The subject consists of 53.8% males and single with age (Mean=15; SD=6.90). Four and 17 days were the shortest and longest incubation periods while one and six days were the shortest and longest onset periods respectively. A total of 24 (93.3%) patients had generalized tetanus. Nail puncture, road traffic accidents, and umbilical infection were the commonest sources of post-neonatal and neonatal tetanus in this study. Spasm is the commonest manifestation, present in 19 (73.1%) of the study population. This is closely followed by trismus in 57.7% of the cases. About half have a positive vaccination history. This study found case fatality of 7.7%. Conclusion: Generalized tetanus was the commonest type seen in this study, while nail puncture, road traffic accident and umbilical infection were the most common sources of infection. Although, more than half of the study subjects received immunization to prevent tetanus, the case fatality in this study was in one in twelve sufferers. Keywords: Epidemiology, review, tetanus, trend. Correspondence:Bello Surajudeen Oyeleke. Department of Paediatrics Dalhatu Araf Specialist Hospital. Shendam Road, PMB 07, Lafia, Nasarawa State. Email: surajudeenbello4@gmail.com. Mobile: +2347064641540.
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尼日利亚纳萨拉瓦州破伤风趋势和流行病学:五年回顾
背景:破伤风是一种疫苗可预防的非传染性疾病,被称为锁牙,其特征是肌肉痉挛。在发达国家,它是一种被遗忘的疾病,但在发展中国家,它仍然是一种具有重要公共卫生意义的传染病。本研究旨在确定其在纳萨拉瓦州的流行病学趋势和结果。对象和方法:回顾性研究使用从三个选定的卫生设施的医疗记录的二手数据,一个横跨州的三个参议院区。所有破伤风患者均纳入,记录不全者排除5例。数据分析是使用社会科学版本23的统计软件包完成的。因变量为破伤风转归,自变量为潜伏期、发病期、破伤风类型、危险因素、疫苗接种史、破伤风表现。结果:男性占53.8%,年龄为15岁,单身;SD = 6.90)。潜伏期最短为4 d,最长为17 d,发病时间最短为1 d,最长为6 d。全身性破伤风24例(93.3%)。在本研究中,指甲穿刺、道路交通事故和脐带感染是新生儿后和新生儿破伤风最常见的来源。痉挛是最常见的表现,在19例(73.1%)的研究人群中出现。紧随其后的是唇腭裂,占57.7%。大约一半的人有积极的疫苗接种史。本研究发现病死率为7.7%。结论:全身性破伤风是本研究中最常见的感染类型,指甲穿刺、道路交通事故和脐部感染是最常见的感染来源。尽管超过一半的研究对象接受了预防破伤风的免疫接种,但在这项研究中,每12名患者中就有1人死亡。关键词:流行病学;回顾;破伤风;通信:Bello Surajudeen Oyeleke。达尔哈图阿拉夫专科医院儿科。申丹路,PMB 07,拉菲亚,纳萨拉瓦州。电子邮件:surajudeenbello4@gmail.com。手机:+ 2347064641540。
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