Congenital heart diseases: Pattern of clinical presentations in children less than 2-years of age in a pediatric practice in southsouth Nigeria

O.J. Osarenkhoe, O.H. Aiwuyo, D. Osaghae
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Abstract

The increase in the prevalence of congenital heart disease remains a major contributing factor tochildhood morbidity and mortality in Africa. The study describes the clinical features of children withCHD that presented to a general pediatric hospital, to improve on early recognition and management ofthe diseases. The prevalence of CHD from the study was 2 per 100 (30 per 1577 or 1 in 52) i.e. (2/100 or20/1000). A higher incidence in females (53.3%) with M: F = 1:1.14, the majority presented withdifficulty / fast breathing (70%), cough(40%), other presenting symptoms are poor weight gain (26.7%),delayed milestones(13.3%). On examination, 60% had dyspnea, 56.7% had murmur. Packed cell volumefor acyanotic heart disease ranged 28-30%, and 50-61% for cyanotic heart disease. The majority hadcomorbid bronchopneumonia (46.6%), and heart failure (23.3%). Echocardiographic findings revealedVSD in 26.7%, 20.0% had PDA and tetralogy of Fallot in 6.7%, Transposition of Great Arteries in 3.3%,and Dextrocardia in 3.3%. The outcome showed that 30% had no symptoms on follow-up, 23.3% werereferred for surgery, 10% dropped from follow-up and 3.3% died. These findings which are comparable tothe findings of other researchers showed that congenital heart disease has a place in childhood morbidityand mortality, therefore appropriate attention should be directed to improve on early recognition andmanagement of the diseases.
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先天性心脏病:两岁以下儿童在尼日利亚南部儿科诊所的临床表现模式
先天性心脏病患病率的增加仍然是非洲儿童发病率和死亡率的一个主要因素。本研究描述了向普通儿科医院提出的冠心病儿童的临床特征,以提高对疾病的早期识别和管理。研究中冠心病的患病率为2/100(30 / 1577或1 / 52),即(2/100或20/1000)。女性发病率较高(53.3%),M: F = 1:1.1 14,大多数表现为呼吸困难/快速(70%),咳嗽(40%),其他表现为体重增加不佳(26.7%),发育里程碑延迟(13.3%)。检查时,60%有呼吸困难,56.7%有杂音。无青绀型心脏病的堆积细胞体积为28-30%,青绀型心脏病的堆积细胞体积为50-61%。大多数合并支气管肺炎(46.6%)和心力衰竭(23.3%)。超声心动图显示室性心动障碍占26.7%,PDA占20.0%,法洛四联症占6.7%,大动脉转位占3.3%,心右位占3.3%。结果显示,随访时无症状者占30%,转诊手术者占23.3%,随访后下降10%,死亡人数占3.3%。这些发现与其他研究者的研究结果相当,表明先天性心脏病在儿童发病率和死亡率中占有一席之地,因此应给予适当的重视,以提高疾病的早期识别和管理。
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