Gastrodin Improves Quality of Life and Outcome of Autoimmune Encephalitis Treatment with High-Dose Gamma Globulin and Collaborative Care

IF 0.4 4区 医学 Q4 NUTRITION & DIETETICS Current Topics in Nutraceutical Research Pub Date : 2023-08-03 DOI:10.37290/ctnr2641-452x.21:417-425
Mengting Yu, Xuefen Li, Junxiong Yin, Yan Huang, Zhaomin Xie, Min Wang, Yunyi Li
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Abstract

This study aims to elucidate the effectiveness of gastrodin in improving the outcome of autoimmune encephalitis patients receiving high-dose gamma globulin plus collaborative nursing care. Gastrodin led to higher post-treatment Mini-mental State Examination scores, CD3+, CD4+, IgA, IgG, and IgM than the control group, and lower inflammatory cytokine levels (P < 0.05). To sum up, gastrodin administration to patients receiving high-dose gamma globulin and collaborative nursing care was highly effective in treating autoimmune encephalitis and can effectively improve patients’ quality of life.
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天麻素改善高剂量丙种球蛋白治疗自身免疫性脑炎患者的生活质量和预后
本研究旨在探讨天麻素对自身免疫性脑炎患者高剂量丙种球蛋白配合护理的疗效。天麻素导致治疗后精神状态检查评分、CD3+、CD4+、IgA、IgG和IgM均高于对照组,炎症细胞因子水平低于对照组(P <0.05)。综上所述,天麻素给予高剂量丙种球蛋白患者配合护理治疗自身免疫性脑炎疗效显著,可有效改善患者的生活质量。
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: Current Topics in Nutraceutical Research is an international, interdisciplinary broad-based peer reviewed scientific journal for critical evaluation of research on chemistry, biology and therapeutic applications of nutraceuticals and functional foods. The major goal of this journal is to provide peer reviewed unbiased scientific data to the decision makers in the nutraceutical and food industry to help make informed choices about development of new products. To this end, the journal will publish two types of review articles. First, a review of preclinical research data coming largely from animal, cell culture and other experimental models. Such data will provide basis for future product development and/or human research initiatives. Second, a critical evaluation of current human experimental data to help market and deliver the product for medically proven use. This journal will also serve as a forum for nutritionists, internists, neurologists, psychiatrists, and all those interested in preventive medicine. The common denominator of all of the topic to be covered by the journal must include nutraceuticals and/functional food. The following is an example of some specific areas that may be of interest to the journal. i) Role of vitamins, minerals, antioxidants and phytonutrients on cardiovascular health, cancer, diabetes, ocular health, mental health, men’s health, women’s health, infant nutrition, ii) Role of herbals on human health, iii) Dietary supplements and sleep, iv) Components of diet that may have beneficial effect on human health, v) regulation of apoptosis and cell viability, vi) Isolation and characterization of bioactive components from functional foods, vii) Nutritional genomics, and viii) Nutritional proteomics.
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