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Enhancing Nutritional Status and Quality of Life in Hemodialysis Patients: The Impact of Internet-Based Cognitive Behavioral Therapy 改善血液透析患者的营养状况和生活质量:基于互联网的认知行为疗法的影响
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-02-10 DOI: 10.37290/ctnr2641-452x.22:538-543
Lu Wang, Hu Yi
This study examined the effects of internet-based cognitive behavioral therapy on the nutritional status and scores from the Knowledge, Attitude, and Practice questionnaire in maintenance hemodialysis patients. Patients in the traditional therapy group received standard health education, whereas those in the experimental group participated in three months of this therapy. Clinical and nutritional indicators, including blood biomarkers and Knowledge, Attitude, and Practice questionnaire scores, were recorded for both groups before and after the treatment. Post-treatment, the group receiving internet-based cognitive behavioral therapy exhibited higher blood calcium levels, increased upper arm circumference, and reduced levels of potassium and phosphorus. They also showed comparatively lower scores in Nutritional Risk Screening 2000 and Malnutrition Inflammation, along with higher Visual Analog Scale scores (P < 0.05). The internet-based cognitive behavioral therapy group exhibited higher albumin and prealbumin levels, reduced transferrin, total cholesterol, creatinine, and urea levels, and modified quantitative subjective global assessment scores than the traditional therapy group (P < 0.05). They also scored higher on the Knowledge, Attitude, and Practice questionnaire (P < 0.05). These results indicate that internetbased cognitive behavioral therapy can improve the nutritional status, Knowledge, Attitude, and Practice questionnaire scores, and overall quality of life in maintenance hemodialysis patients, highlighting its potential benefit in patient outcomes.
本研究探讨了基于互联网的认知行为疗法对维持性血液透析患者的营养状况以及知识、态度和实践问卷得分的影响。传统疗法组的患者接受了标准的健康教育,而实验组的患者则参加了为期三个月的该疗法。治疗前后记录了两组患者的临床和营养指标,包括血液生物标志物和知识、态度与实践问卷得分。治疗后,接受基于互联网的认知行为疗法组的血钙水平升高,上臂围增加,钾和磷水平降低。此外,他们在营养风险筛查 2000 和营养不良性炎症方面的得分也相对较低,视觉模拟量表得分更高(P < 0.05)。与传统疗法组相比,基于互联网的认知行为疗法组的白蛋白和前白蛋白水平更高,转铁蛋白、总胆固醇、肌酐和尿素水平降低,定量主观总体评估得分也有所改善(P < 0.05)。他们在知识、态度和实践问卷中的得分也更高(P < 0.05)。这些结果表明,基于互联网的认知行为疗法可以改善维持性血液透析患者的营养状况、知识、态度和实践问卷得分以及整体生活质量,突出了其对患者预后的潜在益处。
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引用次数: 0
Effect of Preventive Care on Postoperative Rehabilitation and Nutritional Status in Patients with Cerebral Hemorrhage 预防性护理对脑出血患者术后康复和营养状况的影响
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-02-06 DOI: 10.37290/ctnr2641-452x.22:503-508
Lei Wan, Lei Huang, Ke Wang, Jingjing An
Cerebral hemorrhage is a common cerebrovascular disease affecting middle-aged and older adults, with an increasing annual incidence. Surgical removal of intracranial hematomas can save the lives of patients with cerebral hemorrhage. However, surgery-induced stress injuries can severely affect the perioperative nutritional status of patients, leading to an adverse prognosis. This study aimed to examine the effect of preventive care on patients with cerebral hemorrhage to improve patient safety during treatment. We found that patients in the experimental group who received preventive care had substantially improved postoperative rehabilitation quality, a decreased incidence of postoperative adverse reactions, and a shortened hospital stay than those in the control group who received routine care. Furthermore, preventive care reduced the risk of malnutrition and considerably improved the nutritional status of patients with CH. Preventive care can effectively improve the postoperative safety of patients with CH, shorten their rehabilitation cycle, promote their body function recovery, and enhance their nutritional status, which is essential in clinical practice.
脑出血是中老年人常见的脑血管疾病,发病率逐年上升。手术清除颅内血肿可以挽救脑出血患者的生命。然而,手术引起的应激损伤会严重影响患者围手术期的营养状况,导致不良预后。本研究旨在探讨预防性护理对脑出血患者的影响,以提高患者在治疗过程中的安全性。我们发现,与接受常规护理的对照组相比,接受预防性护理的实验组患者术后康复质量大幅提高,术后不良反应发生率降低,住院时间缩短。此外,预防性护理降低了营养不良的风险,大大改善了CH患者的营养状况。预防性护理可有效提高CH患者的术后安全性,缩短其康复周期,促进其身体功能恢复,改善其营养状况,这在临床实践中至关重要。
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引用次数: 0
Natural Products Regulate the P38MAPK Signaling Pathway: A Promising Strategy in the Prevention and Treatment of Alzheimer’s Disease 天然产品可调节 P38MAPK 信号通路:预防和治疗阿尔茨海默病的有效策略
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-01-22 DOI: 10.37290/ctnr2641-452x.22:509-518
Yue Zhu, Mengyuan Qiao, Jinxin Chen, Manru Xu, Wenbin Wu
Alzheimer’s disease is a common neurodegenerative condition that severely affects the quality of life of patients and their families, resulting in a substantial societal burden. In the pathogenesis of Alzheimer’s disease, the p38 mitogen-activated protein kinase pathway is closely associated with neuroinflammation, apoptosis, synaptic plasticity, amyloid beta deposition, and aberrant tau phosphorylation. Natural products have a high potential for therapeutic modulation of the P38 MAPK pathway. We searched PubMed, EMBASE, Medline, and Web of Science, utilizing the keywords “Alzheimer’s disease,” “neurodegenerative diseases,” “MAPK,” and “P38MAPK” and “natural products” to identify natural products that can be used to treat Alzheimer’s disease by modulating the P38MAPK pathway. Various natural products were found to act on p38 MAPK, including saponins, flavonoids, alkaloids, acids, terpenoids, and glycosides. All these active agents can treat Alzheimer’s disease through their interactions with p38 MAPK. This study aimed to examine the use of natural products to intervene in Alzheimer’s disease and regulate the p38 MAPK pathway to provide potential ideas for further drug research and development.
阿尔茨海默病是一种常见的神经退行性疾病,严重影响患者及其家人的生活质量,造成巨大的社会负担。在阿尔茨海默病的发病机制中,p38 丝裂原活化蛋白激酶通路与神经炎症、细胞凋亡、突触可塑性、淀粉样蛋白 beta 沉积和 tau 磷酸化异常密切相关。天然产品在治疗调节 P38 MAPK 通路方面具有很大的潜力。我们以 "阿尔茨海默病"、"神经退行性疾病"、"MAPK"、"P38MAPK "和 "天然产品 "为关键词,对 PubMed、EMBASE、Medline 和 Web of Science 进行了检索,以确定可用于通过调节 P38MAPK 通路治疗阿尔茨海默病的天然产品。研究发现,多种天然产品可作用于 P38MAPK,包括皂苷、黄酮类、生物碱、酸类、萜类和苷类。所有这些活性物质都能通过与 p38 MAPK 的相互作用治疗阿尔茨海默病。本研究旨在探讨利用天然产物干预阿尔茨海默病并调节 p38 MAPK 通路,从而为进一步的药物研究和开发提供潜在的思路。
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引用次数: 0
Dialysis and Nutrition: Optimizing Dietary Support for Patients Undergoing Blood Purification 透析与营养:优化血液净化患者的饮食支持
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-01-19 DOI: 10.37290/ctnr2641-452x.22:473-477
Lei Xiao, Meijuan Zhu, Juan Chen, Li Chen, Mingxia Lin, Huihui Han, Jinrong Wu
This study evaluated the effectiveness of individualized dietary interventions in improving the nutritional status and general health of individuals undergoing dialysis. A total of 120 patients undergoing dialysis were equally allocated to the Standard Care Group and Intervention Group. The recipients of individualized dietary counseling had their plans modified monthly in accordance with their nutritional needs, personal preferences, and clinical circumstances. Nutritional adherence, biochemical parameters, clinical outcomes, and quality of life were evaluated and compared between groups. At baseline, both groups exhibited comparable demographic characteristics. Compared to baseline values, the Intervention Group showed substantial enhancements in albumin, hemoglobin, potassium, and phosphorus levels after six months (P < 0.05). The Intervention Group had a considerably higher rate of adherence to dietary recommendations than the Standard Care Group (92% vs. 75%, P < 0.01). Nutritional intake analyses revealed a noteworthy enhancement in energy and protein consumption, while sodium, potassium, and phosphorus intake decreased (P < 0.05). The results of the quality-of-life evaluation demonstrated notable improvements in physical, emotional, social, and overall health perception scores (P < 0.05). Thus, personalized dietary interventions substantially improve the nutritional status, biochemical profile, and overall quality of life of patients undergoing dialysis.
这项研究评估了个性化饮食干预对改善透析患者营养状况和总体健康的效果。共有 120 名透析患者被平均分配到标准护理组和干预组。接受个体化饮食咨询的患者每月都会根据其营养需求、个人偏好和临床情况修改计划。对两组患者的营养依从性、生化指标、临床疗效和生活质量进行了评估和比较。在基线值上,两组的人口统计学特征相当。与基线值相比,干预组的白蛋白、血红蛋白、钾和磷水平在 6 个月后有显著提高(P < 0.05)。干预组对饮食建议的坚持率大大高于标准护理组(92% 对 75%,P < 0.01)。营养摄入分析显示,能量和蛋白质的摄入量显著增加,而钠、钾和磷的摄入量则有所减少(P < 0.05)。生活质量评估结果显示,身体、情绪、社交和整体健康感知评分均有明显改善(P < 0.05)。由此可见,个性化饮食干预能显著改善透析患者的营养状况、生化指标和整体生活质量。
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引用次数: 0
High-Quality Nursing Combined with Nutritional Intervention Improves Lung Function, Quality of Life, and Compliance of Patients with Lung Cancer After Chemotherapy 优质护理与营养干预相结合可改善肺癌患者的肺功能、生活质量和化疗后的依从性
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-01-14 DOI: 10.37290/ctnr2641-452x.22:478-484
Dongling Hu, Yaning Yang
We investigated the effects of nutritional support combined with high-quality nursing on lung function, quality of life, and compliance of patients with lung cancer after chemotherapy. We enrolled 80 patients with lung cancer admitted to Ankang People’s Hospital between January 2021 and December 2023. The patients in the observation group received scientific nutrition support combined with high-quality nursing, while those in the control group received routine nursing alone. After three months of intervention, we found that patients in the observation group had higher transferrin, PAB, Alb, Hb, CD4+, CD3+, and CD4+/CD8+ levels than those in the control group (P < 0.05). Additionally, patients in the observation group had lower self-rating anxiety scale, self-rating depression scale, pulmonary function index scores, and fewer adverse reactions than those in the control group. Patients in the observation group had higher social function scores, role function scores, physical function scores, cognitive function scores, emotional function scores, and treatment compliance rates than those in the control group (P < 0.05). Scientific nutrition support combined with high-quality nursing for patients with lung cancer during chemotherapy can help improve nutritional status, immunological function, lung function, quality of life, treatment compliance, adverse reactions, and psychological state.
我们研究了营养支持与优质护理相结合对肺癌患者化疗后肺功能、生活质量和依从性的影响。我们选取了 2021 年 1 月至 2023 年 12 月期间安康市人民医院收治的 80 例肺癌患者作为研究对象。观察组患者接受科学的营养支持和优质护理,对照组患者仅接受常规护理。经过三个月的干预,我们发现观察组患者的转铁蛋白、PAB、Alb、Hb、CD4+、CD3+、CD4+/CD8+水平均高于对照组(P < 0.05)。此外,观察组患者的焦虑自评量表、抑郁自评量表、肺功能指数评分均低于对照组,不良反应也少于对照组。观察组患者的社会功能评分、角色功能评分、身体功能评分、认知功能评分、情绪功能评分和治疗依从率均高于对照组(P < 0.05)。肺癌患者化疗期间科学的营养支持与优质护理相结合,有助于改善患者的营养状况、免疫功能、肺功能、生活质量、治疗依从性、不良反应和心理状态。
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引用次数: 0
Effect of Nutritional Interventions on Serum C-reactive Protein Levels in Patients with Periodontitis: A Comprehensive Meta-Analysis 营养干预对牙周炎患者血清 C 反应蛋白水平的影响:综合元分析
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-01-14 DOI: 10.37290/ctnr2641-452x.22:412-418
Liu Jian, Yang Yi, Chen Shan, Taohua Pan
Elevated level of serum C-reactive protein, a systemic inflammation biomarker, is associated with periodontitis, a common inflammatory condition. This meta-analysis aimed to determine the effects of nutritional interventions on serum C-reactive protein levels in patients with periodontitis. We searched the Cochrane Library, PubMed, Scopus, and Web of Science databases according to PRISMA guidelines, including articles published until December 2023. The articles were selected according to predetermined inclusion criteria, and data extraction and quality assessment were conducted utilizing the Newcastle-Ottawa Scale and standardized forms. Seven out of 438 identified articles met the inclusion criteria. We found that patients with periodontitis had a statistically significant correlation between nutritional interventions and decreased serum C-reactive protein levels (p < 0.05). The interventions included specified dietary modifications and dietary supplements, including vitamin C and folic acid. Diverse patient demographics and intervention categories were observed across the identified articles. Thus, this meta-analysis confirmed that nutritional interventions can reduce serum C-reactive protein levels in patients with periodontitis; therefore, dietary modification is essential in managing the systemic inflammation associated with periodontal disease.
血清 C 反应蛋白是一种全身性炎症生物标志物,它的升高与牙周炎这种常见的炎症有关。本荟萃分析旨在确定营养干预对牙周炎患者血清 C 反应蛋白水平的影响。我们根据 PRISMA 指南检索了 Cochrane 图书馆、PubMed、Scopus 和 Web of Science 数据库,包括 2023 年 12 月之前发表的文章。文章按照预先确定的纳入标准进行筛选,并使用纽卡斯尔-渥太华量表和标准化表格进行数据提取和质量评估。在确定的 438 篇文章中,有 7 篇符合纳入标准。我们发现,牙周炎患者的营养干预与血清 C 反应蛋白水平的降低之间存在统计学意义上的显著相关性(P < 0.05)。干预措施包括特定的饮食调整和膳食补充剂,包括维生素 C 和叶酸。在已确定的文章中观察到了不同的患者人口统计学特征和干预类别。因此,这项荟萃分析证实,营养干预措施可降低牙周炎患者的血清 C 反应蛋白水平;因此,调整饮食对控制与牙周疾病相关的全身炎症至关重要。
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引用次数: 0
Evaluation of Nutritional Interventions in Preventing Type 2 Diabetes Mellitus: A Randomized Controlled Trial 评估预防 2 型糖尿病的营养干预措施:随机对照试验
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-01-12 DOI: 10.37290/ctnr2641-452x.22:424-430
Qiuyu Li, Xin Wang, Runqing Lu, Jiaoyang Zheng, Jingjing Chen
This study aimed to evaluate the effectiveness of the structured dietary intervention in reducing the risk of developing type 2 diabetes mellitus and improving associated metabolic health indicators. We included 530 participants randomly assigned to an intervention group with a Mediterranean-style diet and a control group with generic dietary guidelines. The incidence of type 2 diabetes mellitus was the primary outcome, whereas changes in fasting plasma glucose, lipid profiles, and body composition were the secondary outcomes. After 24 months, the incidence of type 2 diabetes mellitus was significantly lower among participants in the intervention group than those in the control group (P < 0.05). Fasting glucose, hemoglobin A1c, total cholesterol, and low-density lipoprotein levels were decreased (P < 0.05), and high-density lipoprotein levels were increased among participants in the intervention group than in those in the control group (P < 0.05). Also, body weight, blood pressure, and body mass index, major negative predictors of fasting glucose levels, were significantly decreased in participants in the intervention group than in those in the control group (P < 0.05), irrespective of other covariates. Dietary intervention substantially reduced the risk of developing type 2 diabetes mellitus and improved glycemic control, lipid profiles, and overall metabolic health.
这项研究旨在评估结构化饮食干预在降低 2 型糖尿病发病风险和改善相关代谢健康指标方面的效果。我们将 530 名参与者随机分配到采用地中海式饮食的干预组和采用通用饮食指南的对照组。2 型糖尿病的发病率是主要结果,空腹血浆葡萄糖、血脂和身体成分的变化是次要结果。24 个月后,干预组参与者的 2 型糖尿病发病率明显低于对照组(P < 0.05)。与对照组相比,干预组参与者的空腹血糖、血红蛋白 A1c、总胆固醇和低密度脂蛋白水平下降(P < 0.05),高密度脂蛋白水平上升(P < 0.05)。此外,体重、血压和体重指数是空腹血糖水平的主要负向预测指标,干预组参与者的体重、血压和体重指数明显低于对照组(P < 0.05),与其他协变量无关。饮食干预大大降低了罹患 2 型糖尿病的风险,改善了血糖控制、血脂状况和整体代谢健康。
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引用次数: 0
Improving Liver Cancer Care: The Effects of Perma-Based Psychological and Nutritional Interventions 改善肝癌护理:基于 Perma 的心理和营养干预的效果
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-01-11 DOI: 10.37290/ctnr2641-452x.22:531-537
Fang Xiang, Lingxue Fu, He Ying, Chunxiao Chen, Yu Huixi
This study aimed to explore the effect of combined psychological and nutritional interventions on anxiety, depression, nutritional status, and quality of life among liver cancer patients implanted with iodine-125 seeds under the PERMA model. A total of 82 liver cancer patients admitted to our hospital were randomly allocated into two groups: a control group receiving routine care and an observation group receiving the aforementioned combined intervention under the PERMA model. The study duration spanned three months, after which the Hospital Anxiety and Depression Scale, Mini Nutritional Assessment-Short Form, and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire scores were compared between the groups. Post-intervention findings revealed that the observation group exhibited significantly higher scores in hospital anxiety and depression assessments compared to the control group. Additionally, the observation group demonstrated a significantly higher proportion of patients with good nutritional status, as per the Mini Nutritional Assessment-Short Form. Furthermore, improvements were observed across all dimensions of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, with the observation group showing significantly higher scores in comparison to the control group. These findings highlight the substantial value of integrating psychological intervention with nutritional support within the PERMA model as a means to enhance clinical nursing practices.
本研究旨在探讨在PERMA模式下,心理和营养联合干预对植入碘-125种子的肝癌患者的焦虑、抑郁、营养状况和生活质量的影响。本院共收治了82名肝癌患者,将其随机分为两组:对照组接受常规护理,观察组接受上述PERMA模式下的联合干预。研究为期三个月,研究结束后比较两组患者的医院焦虑抑郁量表、迷你营养评估简表和欧洲癌症研究与治疗组织生活质量问卷得分。干预后的结果显示,与对照组相比,观察组在医院焦虑和抑郁评估中的得分明显更高。此外,根据迷你营养评估短表,观察组患者营养状况良好的比例明显高于对照组。此外,在欧洲癌症研究和治疗组织生活质量问卷的所有维度上,观察组都有所改善,与对照组相比,观察组的得分明显更高。这些研究结果凸显了在 PERMA 模型中将心理干预与营养支持相结合的重要价值,是加强临床护理实践的一种手段。
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引用次数: 0
Wheat Germ Protein Powder: A Study on the Muscle Soreness Relief of Volleyball Players After Training 小麦胚芽蛋白粉:排球运动员训练后肌肉酸痛缓解研究
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-01-10 DOI: 10.37290/ctnr2641-452x.22:347-351
Sihua Liu, Yuping Liu, Ziran Ma
This paper briefly introduces wheat germ protein powder. The alleviating effect of wheat germ protein powder on muscle soreness was studied on 30 male athletes from the varsity volleyball team at the Faculty of Physical Education, Kunming University of Science and Technology. During the study, the athletes were divided into three groups: Group 1 received a kind of starch placebo, Group 2 received a low dose of wheat germ protein powder, and Group 3 received a high dose of wheat germ protein powder. Subjective pain, knee isokinetic muscle strength, and creatine kinase activity levels were measured at different time points before and after exercise. It was found that athletes who consumed wheat germ protein powder experienced faster alleviation of muscle soreness compared to those who took the starch placebo, and athletes who consumed a high dose of wheat germ protein powder demonstrated faster relief of muscle soreness compared to those who consumed a low dose.
本文简要介绍了小麦胚芽蛋白粉。以昆明理工大学体育学院排球校队的 30 名男运动员为研究对象,研究了小麦胚芽蛋白粉对肌肉酸痛的缓解作用。研究期间,运动员被分为三组:第一组接受一种淀粉安慰剂,第二组接受低剂量的小麦胚芽蛋白粉,第三组接受高剂量的小麦胚芽蛋白粉。在运动前后的不同时间点测量主观疼痛、膝关节等速肌力和肌酸激酶活性水平。结果发现,与服用淀粉安慰剂的运动员相比,服用小麦胚芽蛋白粉的运动员肌肉酸痛缓解得更快;与服用低剂量小麦胚芽蛋白粉的运动员相比,服用高剂量小麦胚芽蛋白粉的运动员肌肉酸痛缓解得更快。
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引用次数: 0
Comparison of Efficacy of Amoxicillin/Clavulanate Potassium and Azithromycin Sequential Therapies on Nutritional Status of Children with Bronchopneumonia 阿莫西林/克拉维酸钾和阿奇霉素序贯疗法对支气管肺炎患儿营养状况的疗效比较
IF 0.5 4区 医学 Q4 Medicine Pub Date : 2024-01-07 DOI: 10.37290/ctnr2641-452x.22:466-472
Guilian Wang
Bronchopneumonia is a highly prevalent respiratory disease among malnourished children and infants, and it is mainly treated with antibiotics. Herein, we compared the efficacy of amoxicillin/clavulanate potassium and azithromycin sequential therapies for bronchopneumonia. We found that amoxicillin/clavulanate potassium had improved clinical efficacy and accelerated rehabilitation in patients with bronchopneumonia. Azithromycin demonstrated superior efficacy in inhibiting inflammation, enhancing nutritional status, and regulating trace element levels. The therapeutic safety profile of the two sequential therapies was broadly consistent. In the treatment of bronchopneumonia, azithromycin and amoxicillin/clavulanate potassium have their advantages and disadvantages. Therefore, the drug selection for children should be based on their specific conditions.
支气管肺炎是营养不良儿童和婴儿中的高发呼吸道疾病,主要采用抗生素治疗。在此,我们比较了阿莫西林/克拉维酸钾和阿奇霉素序贯疗法治疗支气管肺炎的疗效。我们发现,阿莫西林/克拉维酸钾可提高支气管肺炎患者的临床疗效并加快康复。阿奇霉素在抑制炎症、改善营养状况和调节微量元素水平方面的疗效更佳。两种连续疗法的治疗安全性基本一致。在支气管肺炎的治疗中,阿奇霉素和阿莫西林/克拉维酸钾各有优缺点。因此,应根据儿童的具体情况选择药物。
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引用次数: 0
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Current Topics in Nutraceutical Research
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