Ultrasound-guided needle tracking with deep learning: A novel approach with photoacoustic ground truth

IF 7.1 1区 医学 Q1 ENGINEERING, BIOMEDICAL Photoacoustics Pub Date : 2023-12-01 DOI:10.1016/j.pacs.2023.100575
Xie Hui , Praveenbalaji Rajendran , Tong Ling , Xianjin Dai , Lei Xing , Manojit Pramanik
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Abstract

Accurate needle guidance is crucial for safe and effective clinical diagnosis and treatment procedures. Conventional ultrasound (US)-guided needle insertion often encounters challenges in consistency and precisely visualizing the needle, necessitating the development of reliable methods to track the needle. As a powerful tool in image processing, deep learning has shown promise for enhancing needle visibility in US images, although its dependence on manual annotation or simulated data as ground truth can lead to potential bias or difficulties in generalizing to real US images. Photoacoustic (PA) imaging has demonstrated its capability for high-contrast needle visualization. In this study, we explore the potential of PA imaging as a reliable ground truth for deep learning network training without the need for expert annotation. Our network (UIU-Net), trained on ex vivo tissue image datasets, has shown remarkable precision in localizing needles within US images. The evaluation of needle segmentation performance extends across previously unseen ex vivo data and in vivo human data (collected from an open-source data repository). Specifically, for human data, the Modified Hausdorff Distance (MHD) value stands at approximately 3.73, and the targeting error value is around 2.03, indicating the strong similarity and small needle orientation deviation between the predicted needle and actual needle location. A key advantage of our method is its applicability beyond US images captured from specific imaging systems, extending to images from other US imaging systems.

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超声引导针跟踪与深度学习:光声地面真实的新方法
准确的针头引导对于安全和有效的临床诊断和治疗程序至关重要。传统超声引导下的针头插入在一致性和精确可视化方面经常遇到挑战,需要开发可靠的方法来跟踪针头。作为一种强大的图像处理工具,深度学习已经显示出增强美国图像中针的可见性的希望,尽管它依赖于手动注释或模拟数据作为基础事实,可能导致潜在的偏见或在推广到真实的美国图像时遇到困难。光声成像(PA)已经证明了其高对比度针可视化的能力。在本研究中,我们探索了PA成像在不需要专家注释的情况下作为深度学习网络训练的可靠基础真值的潜力。我们的网络(UIU-Net)在离体组织图像数据集上进行了训练,在美国图像中定位针头的精度非常高。针分割性能的评估扩展到以前未见过的离体数据和体内人类数据(从开源数据存储库收集)。具体而言,对于人体数据,修正Hausdorff Distance (MHD)值约为3.73,靶向误差值约为2.03,表明预测针头与实际针头位置具有较强的相似性和较小的针头方向偏差。我们方法的一个关键优势是它的适用性超出了从特定成像系统捕获的美国图像,扩展到从其他美国成像系统获取的图像。
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来源期刊
Photoacoustics
Photoacoustics Physics and Astronomy-Atomic and Molecular Physics, and Optics
CiteScore
11.40
自引率
16.50%
发文量
96
审稿时长
53 days
期刊介绍: The open access Photoacoustics journal (PACS) aims to publish original research and review contributions in the field of photoacoustics-optoacoustics-thermoacoustics. This field utilizes acoustical and ultrasonic phenomena excited by electromagnetic radiation for the detection, visualization, and characterization of various materials and biological tissues, including living organisms. Recent advancements in laser technologies, ultrasound detection approaches, inverse theory, and fast reconstruction algorithms have greatly supported the rapid progress in this field. The unique contrast provided by molecular absorption in photoacoustic-optoacoustic-thermoacoustic methods has allowed for addressing unmet biological and medical needs such as pre-clinical research, clinical imaging of vasculature, tissue and disease physiology, drug efficacy, surgery guidance, and therapy monitoring. Applications of this field encompass a wide range of medical imaging and sensing applications, including cancer, vascular diseases, brain neurophysiology, ophthalmology, and diabetes. Moreover, photoacoustics-optoacoustics-thermoacoustics is a multidisciplinary field, with contributions from chemistry and nanotechnology, where novel materials such as biodegradable nanoparticles, organic dyes, targeted agents, theranostic probes, and genetically expressed markers are being actively developed. These advanced materials have significantly improved the signal-to-noise ratio and tissue contrast in photoacoustic methods.
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