A preliminary study on the application of the two-space nonperiodic asymptotic homogenization method to the EEG forward problem with continuously differentiable coefficient

Roberto Martins da Silva Décio Júnior, A. De Cezaro, Leslie Darien Pérez Fernández, Julián Bravo Castillero
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Abstract

The knowledge on the Electroencephalogram (EEG) forward problem is important to improve the imaging of the neural activity, that is an inverse problem. This paper introduces the study of the EEG forward problem via a nonperiodic homogenization technique: the two-space method. Considering a concentric spheres head model for the brain-skull-scalp medium as an micro-heterogeneous medium, a simplification consisting of a 1D problem in spherical coordinates with continuously differentiable coefficient is considered. The two-space method is applied successfully, and a numerical example shows the convergence of the micro-heterogeneous solution to the one obtained by the two-space method, as was expected. The preliminary conclusion is that this approach for the EEG forward problem with homogenization techniques shows itself as very promising. More experiments should be executed, considering more realistic models for the head.
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将双空间非周期性渐近均质化方法应用于具有连续可变系数的脑电图前向问题的初步研究
脑电图正向问题的认识对于改善神经活动的成像具有重要意义,而神经活动是一个逆问题。本文介绍了利用非周期均匀化技术——二维空间法研究脑电正演问题。将脑-颅-头皮介质的同心球头模型作为微非均质介质,考虑由系数连续可微球坐标系下的一维问题构成的简化问题。成功地应用了双空间方法,并通过数值算例证明了微非均质解与双空间方法解的收敛性。初步的结论是,这种方法对脑电图正演问题的均质化技术显示出自己是非常有前途的。应该进行更多的实验,考虑更现实的头部模型。
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