Multiresidue analysis and health risk assessment of sulfonamides and quinolones from edible Batrachia and other aquatic products

Abstract

Tailless amphibians belonging to the order Batrachia are a significant component of human consumption. However, there is limited literature on the consumption of these amphibians by humans. Therefore, the present work aimed to examine the presence of drug residues in edible Batrachia, and compare them with other aquatic products. We assessed 22 veterinary drug residues, including 12 sulfonamides (SAs) and ten quinolones (QNs), in various aquatic products, including edible Batrachia. To provide a comparative analysis, we referenced literature from China between 2005 and 2020 regarding SAs and QNs detected in aquatic products. Additionally, we calculated the food safety index (IFS) of antibiotics, and conducted a health risk assessment. The findings revealed that the detection rate, average residual amount, and over-standard rate of antibiotics in edible Batrachia were higher than most other aquatic products. Furthermore, the systematic cluster analysis demonstrated that edible Batrachia could serve as a potential sentinel animal, distinguishing them from several other aquatic products. The total IFS of all residues obtained from different aquatic products in the present work was less than 1, thus indicating their safety in terms of public health. Nevertheless, it is essential to conduct detailed investigations into the maximum residues of certain antibiotics in specific aquatic products that exceed the safety limits to understand their impact on human health.