The effectiveness of scientifically based monitoring programs and therapeutic and preventive measures for controlled infectious diseases of animals

A. Poryvaeva, E. Pechura, O. G. Petrova, N. A. Bezborodova, Y. Lysova, D. A. Belousova
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Abstract

The aim of the work was to assess the effectiveness  of  an  improved  monitoring program  for  controlled  infectious  animal diseases  and  individual  vaccination  programs for acute respiratory viral infection in cattle.  To  fulfill  the  tasks  set,  serological studies, PCR diagnostics, bacteriological and coprological methods of examining biological samples from animals were carried out. As a result of the work, the main factors influencing  the  effectiveness  of  vaccine prophylaxis of acute respiratory viral infection in cattle populations have been identified. It was found that in three administrative and  administrative  districts  of  the  Sverdlovsk region, the main factors in 35.1% of cases are violations of the rules of vaccination  of  acute  respiratory  viral  infection  of cattle, in 13.5% of cases - violations of zoo-hygienic  and  veterinary–sanitary  conditions of keeping farm animals. A comprehensive assessment of the effectiveness of individual vaccination programs for cattle against acute respiratory  viral  infection  has  been  carried out, taking into account the epizootological situation in agricultural organizations. It was shown  that  vaccination  of  cattle  against acute respiratory viral infection according to individual  programs  ensured  the  formation of specific immunity in 92.5-95.0% of animals.  The  number  of  immunotolerant  individuals and animals with a low level of immunoreactivity in the physiological group of young  cattle  did  not  exceed  3.5%,  in  the physiological  group  of  adult  animals  – 1.25%.    The  high  efficiency  of  improved scientifically based programs for monitoring, diagnosis, therapeutic, preventive and health measures  to  protect  animals  from  epizootically significant infectious diseases of cattle among  the  populations  of  farm  animals  of the Ural Federal District has been confirmed.
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以科学为依据的动物传染病监控计划及治疗和预防措施的有效性
这项工作的目的是评估改进后的动物传染病控制监测计划和牛急性呼吸道病毒感染个体疫苗接种计划的有效性。 为完成既定任务,开展了血清学研究、PCR 诊断、细菌学和协合学方法来检查动物的生物样本。通过这项工作,确定了影响牛群急性呼吸道病毒感染疫苗预防效果的主要因素。研究发现,在斯维尔德洛夫斯克地区的三个行政区中,35.1%的病例的主要因素是违反牛急性呼吸道病毒感染疫苗接种规定,13.5%的病例是违反饲养农场动物的动物园卫生和兽医卫生条件。根据农业组织的动物流行病学情况,对牛急性呼吸道病毒感染疫苗接种计划的有效性进行了全面评估。结果表明,按照单个方案对牛进行急性呼吸道病毒感染疫苗接种可确保 92.5-95.0% 的动物形成特异性免疫。 在幼牛生理组中,免疫耐受个体和免疫反应水平低的动物数量不超过 3.5%,在成年动物生理组中不超过 1.25%。 在乌拉尔联邦区农场动物群体中,以科学为基础的监测、诊断、治疗、预防和保健措施的改进方案在保护动物免受牛流行性重大传染病侵害方面的高效率已得到证实。
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