Phytochemicals and Phytotherapeutic Studies on Different Parts of Aegle marmelos: A Critical Overview

IF 0.2 Q4 Biochemistry, Genetics and Molecular Biology Research Journal of Biotechnology Pub Date : 2023-12-05 DOI:10.25303/1901rjbt1260148
Y. Murti, K. K. Agrawal
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Abstract

Medicines derived from the bael plant (Aegle marmelos Linn.) have made immense contributions to the treatment of various health-related issues. Scientific studies have validated its use in different diseases like antioxidant, antidiarrheal, gastroprotective, anti-ulcerative colitis, antidiabetic, antibacterial, antiviral, hepatoprotective, cardioprotective and anticancer. Different phytochemicals like furocoumarins, aegeline, marmelosin, marmelin, aegelenine, O-methyl halfordinol, psoralen, alloimperatorin, scopoletin etc. present in different parts of the plant are responsible for the activities. As per the literature survey, there is a need for further experiments (both in vitro and in vivo) to find out the mechanism of action of identified bioactive compounds. The acute toxicity data of this plant extract also revealed the safety of this plant. In this review, it can be concluded that this plant has immense potential to be used in the area of drug design from natural lead molecules.
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关于 Aegle marmelos 不同部位的植物化学物质和植物治疗研究:重要概述
从桦木(Aegle marmelos Linn.)中提取的药物为治疗各种健康相关问题做出了巨大贡献。科学研究已经证实了它在不同疾病中的用途,如抗氧化、止泻、胃肠保护、抗溃疡性结肠炎、抗糖尿病、抗菌、抗病毒、保肝、保心和抗癌。该植物不同部分中的不同植物化学物质,如呋喃香豆素、泽泻苷、橘皮苷、橘皮甙、泽泻宁、O-甲基半淀粉苷、补骨脂素、异泽泻苷、莨菪亭等,都是产生这些活性的原因。根据文献调查,有必要进行进一步的实验(包括体外和体内实验),以找出已确定的生物活性化合物的作用机制。这种植物提取物的急性毒性数据也显示了这种植物的安全性。综上所述,这种植物在利用天然先导分子进行药物设计方面具有巨大的潜力。
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来源期刊
Research Journal of Biotechnology
Research Journal of Biotechnology 工程技术-生物工程与应用微生物
CiteScore
0.60
自引率
0.00%
发文量
192
审稿时长
1.5 months
期刊介绍: We invite you to contribute Research Papers / Short Communications / Review Papers: -In any field of Biotechnology, Biochemistry, Microbiology and Industrial Microbiology, Soil Technology, Agriculture Biotechnology. -in any field related to Food Biotechnology, Nutrition Biotechnology, Genetic Engineering and Commercial Biotechnology. -in any field of Biotechnology related to Drugs and Pharmaceutical products for human beings, animals and plants. -in any field related to Environmental Biotechnolgy, Waste Treatment of Liquids, Soilds and Gases; Sustainability. -in inter-realted field of Chemical Sciences, Biological Sciences, Environmental Sciences and Life Sciences. -in any field related to Biotechnological Engineering, Industrial Biotechnology and Instrumentation. -in any field related to Nano-technology. -in any field related to Plant Biotechnology.
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