A systematic review and meta-analysis on GERD after OAGB: rate, treatments, and success.

IF 3.8 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI:10.1080/17474124.2023.2296992
Amir Hossein Davarpanah Jazi, Shahab Shahabi, Erfan Sheikhbahaei, Salvatore Tolone, Mehdi El Skalli, Ali Kabir, Rohollah Valizadeh, Mohammad Kermansaravi
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Abstract

Introduction: This review aims to investigate the gastroesophageal reflux disease (GERD) as one of the important concerns for both surgeons and patients after one anastomosis gastric bypass (OAGB).

Method: PubMed, Scopus, Embase, Web of Science, and Cochrane were reviewed by the end of the 2021 with keywords relating to GERD, OAGB, and their equivalents. Data regarding OAGB, number of patients with GERD, treatment for GERD, endoscopy findings, the interval between GERD and OAGB were retrieved by two independent investigators. The primary effect/effect size measure was prevalence.

Results: 40 studies examining 17,299 patients were included revealing that 2% of patients experience GERD following OAGB. Reflux after revisional OAGB is six times higher than primary OAGB. Despite being unclear, medical and surgical treatments for GERD after OAGB were used in 60% and 41% of patients with estimated success rate of 85% and 100%, respectively.

Conclusion: Based on how GERD was identified after OAGB, its rate ranged from 0 to 55%; the pooled rate of 2% is near to Roux-en-Y gastric bypass. GERD symptoms can be mild to be tolerated without medical treatment, moderate that respond to acid-reducing agents, or severe enough that are categorized as interactable and would need a surgical intervention.

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关于 OAGB 术后胃食管反流病的系统回顾和荟萃分析:发病率、治疗方法和成功率。
简介:本综述旨在研究胃食管反流病(GERD),该病是单吻合胃旁路术(OAGB)术后外科医生和患者共同关注的重要问题之一:方法:在 2021 年年底之前,对 PubMed、Scopus、Embase、Web of Science 和 Cochrane 进行了检索,检索关键词包括胃食管反流病、OAGB 及其同义词。两名独立研究人员检索了有关 OAGB、胃食管反流患者人数、胃食管反流治疗、内镜检查结果、胃食管反流与 OAGB 之间间隔的数据。效果/效应大小的主要衡量标准是患病率:结果:共纳入了 40 项研究,对 17,299 名患者进行了检查,结果显示 2% 的患者在接受 OAGB 手术后会出现胃食管反流。修正 OAGB 后的反流率是原发性 OAGB 的六倍。尽管尚不明确,但有 60% 和 41% 的患者在 OAGB 术后采用了药物和手术治疗胃食管反流病,估计成功率分别为 85% 和 100%:根据 OAGB 术后胃食管反流病的识别方式,其发生率从 0% 到 55% 不等;2% 的总发生率接近 Roux-en-Y 胃旁路术。胃食管反流症状可以是轻度的,无需药物治疗即可忍受;也可以是中度的,对减酸剂有反应;还可以是重度的,被归类为可相互作用的症状,需要手术治疗。
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来源期刊
Expert Review of Gastroenterology & Hepatology
Expert Review of Gastroenterology & Hepatology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
6.80
自引率
2.60%
发文量
86
审稿时长
6-12 weeks
期刊介绍: The enormous health and economic burden of gastrointestinal disease worldwide warrants a sharp focus on the etiology, epidemiology, prevention, diagnosis, treatment and development of new therapies. By the end of the last century we had seen enormous advances, both in technologies to visualize disease and in curative therapies in areas such as gastric ulcer, with the advent first of the H2-antagonists and then the proton pump inhibitors - clear examples of how advances in medicine can massively benefit the patient. Nevertheless, specialists face ongoing challenges from a wide array of diseases of diverse etiology.
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