Search for crucial events in physiological processes

Yawer Hussain Shah, Paolo Grigolini
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Abstract

The main purpose of this paper is to attract the attention of researchers working in the field of physiological processes, towards crucial events. Crucial events are often confused with extreme events thereby generating the misleading impression that their treatment should be based on quantum mechanical formalism. We show that crucial events are invisible and should not be confused with catastrophes. Crucial events are generated by self-organization processes yielding a form of swarm intelligence, and signal their action with fluctuations characterized by anomalous scaling and 1/f spectrum. The existence or the lack of crucial events can be revealed with an entropic method of analysis called the Diffusion Entropy Analysis (DEA). However, anomalous scaling and 1/f spectrum are not a compelling signature of efficient self-organization, and physiological processes with anomalous scaling and 1/f noise spectrum without crucial events are a signature of collapsing physiological organizations. In the case of physiological processes like cancer dynamics, the existence of crucial events is a signal of intelligence that must be destroyed rather than reinforced.
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寻找生理过程中的关键事件
本文的主要目的是吸引生理过程领域的研究人员关注关键事件。关键事件经常与极端事件混淆,从而给他们造成一种误解,以为应该根据量子力学形式主义来处理它们。我们的研究表明,关键事件是不可见的,不应与灾难混为一谈。关键事件是由自组织过程产生的,是一种群集智能,并以反常缩放和 1/ 谱的波动为特征来表明其作用。然而,异常缩放和1/f频谱并不是有效自组织的显著标志,而具有异常缩放和1/f噪声频谱的生理过程却没有关键事件,这是生理组织崩溃的标志。在癌症动力学等生理过程中,关键事件的存在是智能的信号,必须予以摧毁而不是强化。
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