Temperature Control Strategies of Atmospheric Plasma Jet for Tissue Treatment

IF 4.6 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2023-12-07 DOI:10.1109/TRPMS.2023.3340154
Bingkai Wang;Xu Yan;Zilan Xiong
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Abstract

Besides the charged particles and neutral reactive species, the temperature effect is another significant issue needs to concern during the plasma treatment of biological tissue, which has effects on therapeutic efficacy and the risk of burns. Due to the influence of multiple factors on the temperature effect, it’s a complex nonlinear problem. In this study, temperature rise and distribution uniformity under different parameters and moving trajectories on porcine skin were investigated, and then a surface temperature control strategy was proposed. A 3-D electric motor control platform was constructed for the jet moving during the treatment. First, the effects of factors, such as distance, voltage, and flow rate on temperature variation over porcine skin surface, were analyzed, and the trends of temperature variation under single-factor influence were summarized. Then, the temperature distribution of fixed-point treatment and the temperature superposition effect on the tissue surface under different trajectories were explored, and a trajectory scheme for achieving homogeneous temperature distribution was proposed. Finally, a closed-loop control model was designed to achieve the control objectives of constant temperature holding over a certain surface area and resistance to high-temperature interference in real time. This control scheme also has reference significance for other surface treatments such as material processing.
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用于组织处理的大气等离子体射流温度控制策略
除了带电粒子和中性活性物质,温度效应是等离子体处理生物组织过程中需要关注的另一个重要问题,它对治疗效果和灼伤风险都有影响。由于温度效应受多种因素影响,是一个复杂的非线性问题。本研究对猪皮肤在不同参数和运动轨迹下的温升和分布均匀性进行了研究,并提出了一种表面温度控制策略。为治疗过程中的射流移动搭建了一个三维电机控制平台。首先,分析了距离、电压和流速等因素对猪皮肤表面温度变化的影响,并总结了单因素影响下的温度变化趋势。然后,探讨了不同轨迹下定点治疗的温度分布和组织表面的温度叠加效应,并提出了实现均匀温度分布的轨迹方案。最后,设计了一个闭环控制模型,以实现在一定表面积上保持恒温和实时抗高温干扰的控制目标。该控制方案对材料加工等其他表面处理也具有参考意义。
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来源期刊
IEEE Transactions on Radiation and Plasma Medical Sciences
IEEE Transactions on Radiation and Plasma Medical Sciences RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
8.00
自引率
18.20%
发文量
109
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Affiliate Plan of the IEEE Nuclear and Plasma Sciences Society Table of Contents Introducing IEEE Collabratec IEEE Transactions on Radiation and Plasma Medical Sciences Publication Information Member Get-a-Member (MGM) Program
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