Synthetic-Hydroxyapatite-Based Coatings on the Ultrafine-Grained Titanium and Zirconium Surface

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Abstract

The development of biocompatible materials is a multidisciplinary task and requires the interaction of physicists, chemists, biologists, and physicians, since the functional reliability of materials depends on their biochemical, cellular, tissue, and biomechanical compatibility. This area has been developing intensively in recent years, resulting in numerous research articles. As assumed, the composition of the biocompatible coating of the new generation should coincide as much as possible with the composition of natural human bone and be able to simulate bone tissue on its surface. As a result of the approximation of the phase-structural state and properties of the resulting coatings on implants to the parameters of bone tissue, improved compatibility between them can be achieved. When forming biocompatible coatings, special attention is paid to creating a definite relief (roughness) on the implant surface. There is a current search for new technological solutions for creating a biocompatible rough surface on implants that ensures reliable integration of the implant into bone tissue, since existing technologies do not fully meet state-of-the-art medical requirements.
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超细晶粒钛和锆表面的羟基磷灰石合成涂层
生物兼容材料的开发是一项多学科任务,需要物理学家、化学家、生物学家和医生的共同参与,因为材料的功能可靠性取决于其生化、细胞、组织和生物力学兼容性。近年来,这一领域一直在蓬勃发展,发表了大量研究文章。根据假设,新一代生物相容性涂层的成分应尽可能与天然人体骨骼的成分相吻合,并能在其表面模拟骨组织。由于植入物涂层的相结构状态和特性接近于骨组织参数,因此可以提高它们之间的兼容性。在形成生物相容性涂层时,要特别注意在种植体表面形成一定的凹凸(粗糙度)。由于现有技术不能完全满足最先进的医疗要求,因此目前正在寻找新的技术解决方案,在植入物上形成生物相容性粗糙表面,确保植入物与骨组织可靠结合。
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